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  1. Research article

    Incidence and diagnosis of Acute kidney injury in hospitalized adult patients: a retrospective observational study in a tertiary teaching Hospital in Southeast China

    Acute kidney injury (AKI) places a heavy burden on the healthcare system in China and is usually misdiagnosed. However, there are limited studies that have described the epidemiology and diagnosis of AKI in Ch...

    Xiaoyan Cheng, Buyun Wu, Yun Liu, Huijuan Mao and Changying Xing

    BMC Nephrology 2017 18:203

    Published on: 24 June 2017

  2. Research article

    C-terminal fragment of agrin (CAF) levels predict acute kidney injury after acute myocardial infarction

    Patients with acute myocardial infarction are at high risk for acute kidney injury. Novel biomarkers that can predict acute kidney injury in AMI may allow timely interventions. C-terminal fragment of agrin (CA...

    Spyridon Arampatzis, Georgios Chalikias, Vasilios Devetzis, Stavros Konstantinides, Uyen Huynh-Do and Dimitrios Tziakas

    BMC Nephrology 2017 18:202

    Published on: 24 June 2017

  3. Research article

    Membranous nephropathy: a retrospective observational study of membranous nephropathy in north east and central London

    Membranous nephropathy (MN) is the leading cause of nephrotic syndrome in adults. MN is a clinically heterogeneous disease and it is difficult to accurately predict outcomes (including end stage renal failure)...

    Sanjana Gupta, John Connolly, Ruth J Pepper, Stephen B Walsh, Magdi M Yaqoob, Robert Kleta and Neil Ashman

    BMC Nephrology 2017 18:201

    Published on: 21 June 2017

  4. Research article

    Screening for chronic kidney disease of uncertain aetiology in Sri Lanka: usability of surrogate biomarkers over dipstick proteinuria

    The use of dipstick proteinuria to screen Chronic Kidney Disease of uncertain aetiology (CKDu) in Sri Lanka is a recently debated matter of dispute. The aim of this study was to assess the suitability of bioma...

    Samantha Ratnayake, Zeid Badurdeen, Nishantha Nanayakkara, Tilak Abeysekara, Neelakanthi Ratnatunga and Ranjith Kumarasiri

    BMC Nephrology 2017 18:199

    Published on: 19 June 2017

  5. Review

    Treatment decisions for older adults with advanced chronic kidney disease

    Dialysis initiation rates among older adults, aged 75 years or greater, are increasing at a faster rate than for younger age groups. Older adults with advanced CKD (eGFR < 30 ml/min/1.73 m2) typically lose renal ...

    Steven J. Rosansky, Jane Schell, Joseph Shega, Jennifer Scherer, Laurie Jacobs, Cecile Couchoud, Deidra Crews and Matthew McNabney

    BMC Nephrology 2017 18:200

    Published on: 19 June 2017

  6. Research article

    Effects of home-based exercise on pre-dialysis chronic kidney disease patients: a randomized pilot and feasibility trial

    Only a few research is available on the effects of home-based exercise training on pre-dialysis chronic kidney disease (CKD) patients. Therefore, we aimed to elucidate the effect of home-based exercise therapy...

    Koji Hiraki, Yugo Shibagaki, Kazuhiro P. Izawa, Chiharu Hotta, Akiko Wakamiya, Tsutomu Sakurada, Takashi Yasuda and Kenjiro Kimura

    BMC Nephrology 2017 18:198

    Published on: 17 June 2017

  7. Research article

    Religious coping methods predict depression and quality of life among end-stage renal disease patients undergoing hemodialysis: a cross-sectional study

    Poor quality of life (QOL) and a high prevalence of depression have been identified among end-stage renal disease (ESRD) patients undergoing hemodialysis (HD). We aimed to evaluate the associations between rel...

    Paulo Roberto Santos, José Roberto Frota Gomes Capote Júnior, José Renan Miranda Cavalcante Filho, Ticianne Pinto Ferreira, José Nilson Gadelha dos Santos Filho and Stênio da Silva Oliveira

    BMC Nephrology 2017 18:197

    Published on: 17 June 2017

  8. Research article

    Renin-angiotensin system blockers and residual kidney function loss in patients initiating peritoneal dialysis: an observational cohort study

    Although angiotensin-converting enzyme inhibitors (ACEI) and angiotensin-II receptor blockers (ARB) have been shown to preserve residual kidney function in a select group of Asian patients undergoing continuou...

    Jenny I. Shen, Anjali B. Saxena, Sitaram Vangala, Satvinder K. Dhaliwal and Wolfgang C. Winkelmayer

    BMC Nephrology 2017 18:196

    Published on: 17 June 2017

  9. Research article

    Unusual clinical outcome of primary Hyperoxaluria type 1 in Tunisian patients carrying 33_34InsC mutation

    Primary hyperoxaluria type 1 (PH1), is a rare and heterogeneous disease and one of major causes of renal insufficiency in Tunisia, caused by mutations in the AGXT gene. 33-34InsC mutation, was mainly described in...

    Ibtihel Benhaj Mbarek, Saoussen Mdimeg, Amira Moussa, Dorsaf Zellama, Hayat Kaarout, Jaouida Abdelmoula, Abdellatif Achour, Saoussen Abroug, Asma Omezzine and Ali Bouslama

    BMC Nephrology 2017 18:195

    Published on: 15 June 2017

  10. Research article

    Protective effect of rutin supplementation against cisplatin-induced Nephrotoxicity in rats

    Cisplatin (CP) is commonly used in the treatment of different types of cancer but nephrotoxicity has been a major limiting factor. Therefore, the present study aimed to study the possible protective effect of ...

    Ali R. Alhoshani, Mohamed M. Hafez, Sufia Husain, Abdel Malek Al-sheikh, Moureq R. Alotaibi, Salim S. Al Rejaie, Musaad A. Alshammari, Mashal M. Almutairi and Othman A. Al-Shabanah

    BMC Nephrology 2017 18:194

    Published on: 15 June 2017

  11. Research article

    Metabolic syndrome is independently associated with a mildly reduced estimated glomerular filtration rate: a cross-sectional study

    Association between metabolic syndrome (MS) and mildly reduced estimated glomerular filtration rates (eGFRs) remains unclear. Therefore, we aimed to evaluate the association between MS and a mildly reduced eGF...

    Wen Hu, Xiao-Juan Wu, Yao-Jun Ni, Hai-Rong Hao, Wei-Nan Yu and Hong-Wen Zhou

    BMC Nephrology 2017 18:192

    Published on: 13 June 2017

  12. Research article

    Reduced Kidney Function, Albuminuria, and Risks for All-cause and Cardiovascular Mortality in China: A Population-based Cohort Study

    Previous studies have indicated that reduced kidney function and albuminuria are associated with increased risk of mortality and adverse cardiovascular outcomes, however, the evidence from the Asian population...

    Jinwei Wang, Fang Wang, Shiwei Liu, Maigeng Zhou, Luxia Zhang and Minghui Zhao

    BMC Nephrology 2017 18:188

    Published on: 7 June 2017

  13. Research article

    High Dephosphorylated-Uncarboxylated MGP in Hemodialysis patients: risk factors and response to vitamin K2, A pre-post intervention clinical trial

    Vascular calcifications are highly prevalent in hemodialysis patients. Dephosphorylated-uncarboxylated MGP (dp-ucMGP) was found to increase in vitamin K-deficient patients and may be associated with vascular c...

    Mabel Aoun, Maha Makki, Hiba Azar, Hiam Matta and Dania Nehme Chelala

    BMC Nephrology 2017 18:191

    Published on: 7 June 2017

  14. Research article

    Safety of low-molecular-weight heparin compared to unfractionated heparin in hemodialysis: a systematic review and meta-analysis

    Low molecular weight heparins (LMWH) have been extensively studied and became the treatment of choice for several indications including pulmonary embolism. While their efficacy in hemodialysis is considered si...

    Hind Harrak Lazrak, Émilie René, Naoual Elftouh, Martine Leblanc and Jean-Philippe Lafrance

    BMC Nephrology 2017 18:187

    Published on: 7 June 2017

  15. Research article

    The incidence, risk factors and in-hospital mortality of acute kidney injury in patients after abdominal aortic aneurysm repair surgery

    Acute kidney injury (AKI) is a severe complication associated with abdominal aortic aneurysm (AAA) repair. In this study, we evaluated the incidence, risk factors and in-hospital mortality of AKI in patients a...

    Ying Tang, Junzhe Chen, Kai Huang, Dan Luo, Peifen Liang, Min Feng, Wenxin Chai, Erik Fung, Hui Yao Lan and Anping Xu

    BMC Nephrology 2017 18:184

    Published on: 31 May 2017

  16. Research article

    Urinary TIMP-2 and IGFBP7 for the prediction of acute kidney injury following cardiac surgery

    Acute kidney injury (AKI) following cardiac surgery is common and associated with poor patient outcomes. Early risk assessment for development of AKI remains a challenge. The combination of urinary tissue inhi...

    Yimei Wang, Zhouping Zou, Jifu Jin, Jie Teng, Jiarui Xu, Bo Shen, Wuhua Jiang, Yamin Zhuang, Lan Liu, Zhe Luo, Chunsheng Wang and Xiaoqiang Ding

    BMC Nephrology 2017 18:177

    Published on: 30 May 2017

  17. Research article

    Assessment of physical activity, capacity and nutritional status in elderly peritoneal dialysis patients

    This study aimed to evaluate the prevalence of sedentarism, and to assess physical capacity and nutritional status in a cohort of older patients on peritoneal dialysis (PD), with respect to age-matched non-dialys...

    Adamasco Cupisti, Claudia D’Alessandro, Viviana Finato, Claudia Del Corso, Battista Catania, Gian Marco Caselli and Maria Francesca Egidi

    BMC Nephrology 2017 18:180

    Published on: 30 May 2017

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