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Table 2 The sample sizes required under the additive and multiplicative models for the secondary outcome – functional patency

From: Preventing AVF thrombosis: the rationale and design of the Omega-3 fatty acids (Fish Oils) and Aspirin in Vascular access OUtcomes in REnal Disease (FAVOURED) study

  Total sample size
  Additive model Multiplicative model
Patency failure rate at 6 months for placebo group unadjusted adjusted unadjusted adjusted
40% 874 1455 1156 1812
50% 620 1034 820 1297
60% 452 752 596 941
  1. (Unadjusted and adjusted refer to the calculations of sample size without and with adjustment for loss to follow-up (5%), drop-in (15%) and drop-out (5%))
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