Preventing AVF thrombosis: the rationale and design of the Omega-3 fatty acids (Fish Oils) and Aspirin in Vascular access OUtcomes in REnal Disease (FAVOURED) study

Table 2 The sample sizes required under the additive and multiplicative models for the secondary outcome – functional patency

	Total sample size
	Additive model		Multiplicative model
Patency failure rate at 6 months for placebo group	unadjusted	adjusted	unadjusted	adjusted
40%	874	1455	1156	1812
50%	620	1034	820	1297
60%	452	752	596	941

(Unadjusted and adjusted refer to the calculations of sample size without and with adjustment for loss to follow-up (5%), drop-in (15%) and drop-out (5%))

ISSN: 1471-2369