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Table 3 Effect of being an offspring of a BEN patient on the level of C-reactive protein#

From: Offspring of parents with Balkan Endemic Nephropathy have higher C-reactive protein levels suggestive of inflammatory processes: a longitudinal study

  Repeated measurement-analysis:
200 participants, 349 observations
  Model comparing offspring BEN status Model comparing parental history of BEN
  Parameter
Estimate¥
p-value (t-test) Parameter
Estimate
p-value (t-test)
Offspring of BEN patient vs offspring of control patient 0.102 0.043 -  
Parental history of BEN:     
both -   0.189 0.01
mother -   0.146 0.03
father -   0.013 0.85
none -   Reference  
Age (years) 0.012 < 0.0001 0.01 0.0005
Gender (female) 0.073 0.178 0.06 0.26
Body-mass index 0.038 < 0.0001 0.038 < 0.0001
Smoking in the last 12 months 0.157 0.007 0.153 0.009
  1. # CRP (mg/dL) is log 10 transformed
  2. ¥ Statistically controlled for ex-smoking, history of pyelonephritis, cystitis, other kidney diseases
  3. † Statistically controlled for ex-smoking, history of cystitis, administration of steroid hormones