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Table 2 Transcripts represented by SAGE tags enriched 10 – 30 fold in glomeruli

From: A human glomerular SAGE transcriptome database

Symbol Gene Name NlaIII long Tag Sau3A Tag G:TPM
Sau3A
G:TPM
NlaIII
P:TPM
NlaIII
K:TPM
NlaIII
Ratio
G: P
Ratio
G: K
Link
SAGE Genie
Ref
Link
COL4A4 Collagen, type IV, alpha 4 TAACTTTTGCAAGATGC    122 4 0 29   COL4A4 Ref:COL4A4
AQP1 Aquaporin 1 AGCTCCTGATCAGAGGC    102 4 0 27   AQP1 AQP1
NPR1 Natriuretic peptide receptor A/guanylate cyclase A AGCAGAGACAATTAAAA    163 6 24 27 7 NPR1 NPR1
PTGDS Prostaglandin D2 synthase 21kDa ACGGAACAATAGGACTC CCGGCCAGCC 5,323 2,368 88 24 27 99 PTGDS  
CRHBP Corticotropin releasing hormone binding protein AATAAATACATTCAGAA ATAGTTCTAA 654 286 11   27   CRHBP  
TNNI1 Troponin I type 1 (skeletal, slow) AGGCACCTGGGGCTTCT TGCGGGCCAA 158 204 8 24 26 9 TNNI1  
ODZ2 Odz, odd Oz/ten-m homolog 2 ACAGTCACCACGAGGAG    122 5   26   ODZ2  
EPAS1 Endothelial PAS domain protein 1 GAACTTTTCTGTAATGG    82 3 48 24 2 EPAS1  
PODXL Podocalyxin-like GAGGACACAGATGACTC ATATATGTCT 2,323 3,369 141 48 24 70 PODXL Ref:PODXL
TMEM204 Transmembrane protein 204 CGTGCGAGACACGTGTG    204 9   23   TMEM204  
SMAD6 SMAD family member 6 TCTCCGGACGCCACCAA    163 7   23   SMAD6 Ref:Samd6
CLEC3B C-type lectin domain family 3, member B ACCGGCGCCCGCATCGC GTGTAGCCGG 361 367 16 72 23 5 CLEC3B  
IFITM3 Interferon induced transmembrane protein 3 AACCCCTGCTGCCTGGG    102 4   23   IFITM3  
HOXA7 Homeobox A7 GTATGTTGTCTTGAGTT    82 4   21   HOXA7  
CHI3L1 Chitinase 3-like 1 (cartilage glycoprotein-39) GTATGGGCCCTGGACCT CCCAAGCCTG 564 1,021 48   21   CHI3L1  
FRY Furry homolog (Drosophila) TGAACTTGTTGCACTGC    408 19   21   FRY  
PEA15 Phosphoprotein enriched in astrocytes 15 TCTGCCCTTTTTTGTGG    125 6 24 21 5 PEA15  
ZNF250 Zinc finger protein 250 TGGAACCACAAGCAGCC    143 7   20   ZNF250  
TGFBR3 Transforming growth factor, beta receptor III GCAAATCCTGTCGGTCT CTCCTGTCTA 180 122 6   20   TGFBR3  
IGFBP5 Insulin-like growth factor binding protein 5 GAGTACGTTGACGGGGA TTTGTCTTTT 3,496 367 18   20   IGFBP5 Ref:IGFBP5
FCN3 Ficolin (collagen/fibrinogen domain containing) 3 GACACCGAGGGGGGCGG GTCAGCCACC 180 715 36 48 20 15 FCN3  
LRRC32 Leucine rich repeat containing 32 (GARP gene) TTGCATACCCTGACCCC TTTGAAAACA 180 20 1   19   LRRC32  
NOSTRIN Nitric oxide synthase trafficker CCACACGCAGATTCACT TTTGAATGGG 158 61 3   19   NOSTRIN Ref:Nostrin
HTRA1 HtrA serine peptidase 1 TTTCCCTCAAAGACTCT    1,409 74 24 19 59 HTRA1  
ITGA1 Pelota homolog (Drosophila) TGCCAGGTGCAGTCACA    122 6 24 19 5 ITGA1  
TNNC1 Troponin C type 1 (slow) TCCTCAACCCCAAATCC    184 11   17   TNNC1  
DOPEY2 Dopey family member 2 AGAATTGCTTGAACCCA    1,347 79 263 17 5 DOPEY2  
FOXC1 Forkhead box C1 AGCCTGTACGCGGCCGG ATTGTTAAAG 519 245 15 24 17 10 FOXC1  
CEP3 CDC42 effector protein (Rho GTPase binding) 3 ATGCTTCTGCAGAGACT TTGGGCCCTC 226 163 10   17   CEP3  
BGN Biglycan GCCTGTCCCTCCAAGAC GAGAACGGGA 158 776 48 72 16 11 BGN Ref:BGN
MAGI2 Membrane associated guanylate kinase TATTAATAGTCACAGAA    102 7   16   MAGI2  
AIF1L Allograft inflammatory factor 1-like GGAGTGTGCGTGGACTG    1,572 102 334 15 5 C9orf58  
KCNH3 Potassium voltage-gated channel, subfamily H, member 3 TGCCCCTGCCTCTACCT    163 11   15   KCNH3  
PARD6G Par-6 partitioning defective 6 homolog gamma (C. elegans) TCGTTCAGTGCCCCAGC    82 5   15   PARD6G  
TM4SF18 Transmembrane 4 L six family member 18 CAAGTATACCACCCTTC    82 5   15   TM4SF18  
TENC1 Tensin like C1 domain containing phosphatase (tensin 2) AATAGGGGAAAAAAGAG ACATGAATAG 519 531 37   15   TENC1 Ref:TENC1
DPP6 Dipeptidyl-peptidase 6 ACATTTGGTTAAAAAAA    82 6   14   DPP6  
NES Nestin TGCTGACTCCCCCCATC    2,001 138 72 14 28 NES Ref:NES
ADORA1 Adenosine A1 receptor TGACTAATAAAAAACTG    82 6   14   ADORA1 Ref:ADORA1
VEGFA Vascular endothelial growth factor A TTTCCAATCTCTCTCTC CCCTGGCTCC 248 1,450 109 24 13 61 VEGFA Ref:VEGFA
ZNF135 Zinc finger protein 135 GGGAAACTCCATCTCTA    102 8   13   ZNF135  
SLC48A1 Solute carrier family 48 (heme transporter), member 1 GTGCATCAGAGCGGGAA    82 6   13   SLC48A1  
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 GGGTAGTGTCAGTCGGA    122 10 72 13 2 FARP1  
C1orf115 Chromosome 1 open reading frame 115 TCGAAGATTCACTGGGA    102 8 24 12 4 C1orf115  
DAG1 Dystroglycan 1 (dystrophin-associated glycoprotein 1) CAGAGACGTGGCTGGCC    1,286 104 48 12 27 DAG1 Ref:DAG1
PPAP2A Phosphatidic acid phosphatase type 2A AAACACCAACAACTGGG CAGATTGGTC 248 286 23   12   PPAP2A Ref:PPA2A
SEMA3B Semaphorin 3B TGCCGCCCGCAGCCTGC    612 50 72 12 9 SEMA3B  
CDC14A CDC14 cell division cycle 14 homolog A (S. cerevisiae) TATTTTGTTATGAATAG    143 12 24 12 6 CDC14A  
CIRBP Cold inducible RNA binding protein TGCCCGGGGAATGTTCC    82 7   12   CIRBP  
CSRP1 Cysteine and glycine-rich protein 1 CAGGCGGGGTCCTAGGA    82 7   12   CSRP1  
FAM20C Family with sequence similarity 20, member C CGCCCGTCGTGAATTCA    367 31 119 12 3 FAM20C  
CLEC16A C-type lectin domain family 16, member A CTTCGTGGGTACTGAAC    122 10 24 12 5 CLEC16A  
INF2 Inverted formin, FH2 and WH2 domain containing TCCAGCCCCTGAAGTTG    184 16 48 12 4 INF2  
BMP7 Bone morphogenetic protein 7 TGGAACCCGGTCTTGTG    204 18   12   BMP7 Ref:BPM7
ZDHHC6 Zinc finger, DHHC-type containing 6, transmembrane protein 4 TGGTACTTCTCTTTTCC AATGGATGTT 1,128 592 51   12   ZDHHC6  
PPAP2B Phosphatidic acid phosphatase type 2B ATGTAGGTGCCACCCAC AACCACATGC 654 184 16 119 11 2 PPAP2B Ref:PPA2B
TXNIP Thioredoxin interacting protein AGAAACTAGAGGGCAGG    102 9   11   TXNIP  
ITGA3 Integrin, alpha 3 GTACTGTAGCAGGGGAA CTCCACAGAG 180 817 72 24 11 34 ITGA3 Ref:ITGA3
C19orf63 Chromosome 19 open reading frame 63 AAAGAGTCGGGGCTGGA    82 7 48 11 2 C19orf63  
IGFBP2 Insulin-like growth factor binding protein 2, 36kDa GCCTGTACAACCTCAAA CAGGGAGCCC 880 1,797 161 96 11 19 IGFBP2 Ref:IGFBP2
PTGER4 Prostaglandin E receptor 4 (subtype EP4) TTTTGTTGCTCAGTGTT    306 28   11   PTGER4  
FLRT3 Fibronectin leucine rich transmembrane protein 3 TATTTTTCTAGGCATAA    82 8 24 11 3 FLRT3  
VWA1 Von Willebrand factor A domain containing 1 CCCAGGACACCAGCTGG    531 49 24 11 22 VWA1  
LARGE Like-glycosyltransferase AAAGCCCAGTTCTGAAG    82 8 24 11 3 LARGE  
LINGO1 Leucine rich repeat and Ig domain containing 1 AAGATGATATGAGGCCG    122 12   10   LINGO1  
MYO1E Myosin IE TATGAATGTACTAAGTA ATATACTGTA 248 245 26   9   MYO1E Ref:MYO1E
  1. Transcripts represented by SAGE tags enriched 10 – 30 fold in glomeruli compared to pooled SAGE libraries. The gene symbol and gene name are shown for each unique NlaIII-anchored long SAGE tag sequence. Where available, the corresponding short Sau3A SAGE tag (Ref 9) is shown. SAGE tag frequencies are shown as Tags per Million (TPM). Sau3A TPM is derived from Ref 9. Enrichment in glomeruli relative to pooled libraries (G:P) and relative to whole kidney (G:K) is shown for each tag. This table with embedded links to SAGE Genie and links to references showing expression and/or function in glomeruli is provided as additional file 4