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Table 4 Assessment of GFR changes with time using the original Cockcroft and Gault formula (CG), the BSA-modified-Cockcroft and Gault formula (BSA-CG) and the Abbreviated MDRD equation (A-MDRD), and the Mayo Clinic Quadratic equation.

From: Accuracy and limitations of equations for predicting the glomerular filtration rate during follow-up of patients with non-diabetic nephropathies

   Original Cockcroft and Gault formula (CG) BSA-modified-Cockcroft and Gault formula (BSA-CG) Abbreviated MDRD equation (A-MDRD) Mayo Clinic Quadratic equation (MCQ)
Subgroup of patients with deteriorating renal function
(n = 65)
Spearman Correlation coefficient (95% confidence interval) with inulin clearance r = 0.64 (0.43 – 0.78) r = 0.67 (0.46 – 0.80) r = 0.63 (0.41 – 0.78) r = 0.49 (0.23 – 0.69)
  Patients correctly classified as having deteriorating renal function 74% 77% 75% 74%
  Bias (SD of bias) versus inulin clearance 0.98 (6.08) 1.37 (6.88) 1.30 (5.95) 1.32 (13.61)
Subgroup of patients with improving renal function
(n = 61)
Spearman Correlation coefficient (95% confidence interval) inulin clearance 0.75 (0.58 – 0.86) r = 0.75 (0.58 – 0.86) r = 0.72 (0.54 – 0.84) r = 0.46 (0.19 – 0.67)
  Patients correctly classified as having improving renal function 74% 74% 66% 68%
  Bias (SD of bias) versus inulin clearance 3.08 (7.98) 2.98 (7.63) 1.27 (8.87) 3.02 (15.46)