Table 4 Assessment of GFR changes with time using the original Cockcroft and Gault formula (CG), the BSA-modified-Cockcroft and Gault formula (BSA-CG) and the Abbreviated MDRD equation (A-MDRD), and the Mayo Clinic Quadratic equation.
Original Cockcroft and Gault formula (CG) | BSA-modified-Cockcroft and Gault formula (BSA-CG) | Abbreviated MDRD equation (A-MDRD) | Mayo Clinic Quadratic equation (MCQ) | ||
|---|---|---|---|---|---|
Subgroup of patients with deteriorating renal function (n = 65) | Spearman Correlation coefficient (95% confidence interval) with inulin clearance | r = 0.64 (0.43 – 0.78) | r = 0.67 (0.46 – 0.80) | r = 0.63 (0.41 – 0.78) | r = 0.49 (0.23 – 0.69) |
Patients correctly classified as having deteriorating renal function | 74% | 77% | 75% | 74% | |
Bias (SD of bias) versus inulin clearance | 0.98 (6.08) | 1.37 (6.88) | 1.30 (5.95) | 1.32 (13.61) | |
Subgroup of patients with improving renal function (n = 61) | Spearman Correlation coefficient (95% confidence interval) inulin clearance | 0.75 (0.58 – 0.86) | r = 0.75 (0.58 – 0.86) | r = 0.72 (0.54 – 0.84) | r = 0.46 (0.19 – 0.67) |
Patients correctly classified as having improving renal function | 74% | 74% | 66% | 68% | |
Bias (SD of bias) versus inulin clearance | 3.08 (7.98) | 2.98 (7.63) | 1.27 (8.87) | 3.02 (15.46) |