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Table 3 Results of Multivariable Models for Time to Cardiac, Stroke, Mortality and Composite Events [Hazard Ratio (95% Confidence Interval)].

From: CKD classification based on estimated GFR over three years and subsequent cardiac and mortality outcomes: a cohort study

 

Cardiac

Stroke

Mortality

Composite

eGFR < 60

1.38 (1.15, 1.65)

1.49 (1.18, 1.87)

1.83 (1.61, 2.08)

1.58 (1.41, 1.77)

eGFR Decline

1.20 (1.00, 1.45)

1.51 (0.97, 2.35)

1.42 (1.24, 1.64)

1.32 (1.17, 1.49)

eGFR Increase

1.25 (0.88, 1.77)

1.25 (0.97, 1.61)

1.21 (0.91, 1.62)

1.09 (0.85, 1.40)

eGFR ≥60

Reference

Reference

Reference

Reference

  1. Models are adjusted for age, sex, race, study, education, diabetes, history of cardiovascular disease, history of hypertension, alcohol use, smoking status, systolic blood pressure, waist-to-hip ratio, left ventricular hypertrophy, non-HDL cholesterol, and albumin.
  2. Differences between eGFR increase and decline groups non-significant for cardiac (p = 0.86), stroke (p = 0.45), mortality (p = 0.31), and composite (0.16) outcomes.