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Table 6 Results of Multivariable Models for Time to Cardiac, Stroke, Mortality and Composite Events [Hazard Ratio (95% Confidence Interval)] with eGFR groups determined using the CKD-EPI estimating equation.

From: CKD classification based on estimated GFR over three years and subsequent cardiac and mortality outcomes: a cohort study

 

Cardiac

Stroke

Mortality

Composite

eGFR < 60

1.41 (1.15, 1.65)

1.47 (1.15, 1.86)

1.81 (1.59, 2.08)

1.60 (1.42, 1.80)

eGFR Decline

1.14 (0.94, 1.39)

1.25 (0.97, 1.62)

1.52 (1.32, 1.75)

1.35 (1.19, 1.52)

eGFR Increase

1.50 (1.04, 2.19)

1.57 (0.96, 2.55)

1.34 (0.98, 1.82)

1.30 (0.99, 1.70)

eGFR ≥60

Reference

Reference

Reference

Reference

  1. Models are adjusted for age, sex, race, study, education, diabetes, history of cardiovascular disease, history of hypertension, alcohol use, smoking status, systolic blood pressure, waist-to-hip ratio, left ventricular hypertrophy, non-HDL cholesterol, and albumin.