Risk factors for chronic kidney disease in Japan: a community-based study

BMC Nephrology

Table 5 Risk factors for different values of eGFR*

	eGFR, mL/min/1.73 m²
	<60		60--89
Variables	Odds ratio (95%CI)†	p value	Odds ratio (95%CI)†	p value
Ages (each 1 year older age)	1.21 (1.16--1.26)	0	1.07 (1.06--1.08)	0
Male	4.33 (1.37--13.74)	0.013	1.00 (0.65---.54)	0.983
BMI (kg/m²)
(≥ 25 versus <25)	1.32 (0.59--2.97)	0.503	1.23 (0.85--1.79)	0.28
HbA_1c (%)
(>5.8 versus ≤ 5.8)	1.08 (0.37--3.19)	0.885	0.59 (0.33--1.06)	0.077
U-ALB Ratio (mg/g)
(>17.9 versus ≤ 17.9)	1.03 (0.48--2.20)	0.94	0.80 (0.54--1.18)
U-Col4 Ratio (μg/g)				0.255
(>8.2 versus ≤ 8.2 in males, >9.4 versus ≤ 9.4 in females)	0.51 (0.23--1.14)	0.101	0.59 (0.41--0.85)	0.005
Hypertension	2.49 (1.26--4.91)	0.009	1.47 (1.00--2.16)	0.049
Hyperlipidemia	7.86 (3.16--19.59)	0	2.12 (1.24--3.64)	0.006
Alcohol intake	1.11 (0.54--2.27)	0.779	0.87 (0.63--1.20)	0.403
Smoking habit	1.76 (0.57--5.39)	0.323	0.82 (0.55--1.24)	0.343

*An eGFR ≥ 90 was used as the control group. Multilogistic regression was used for statistical comparisons.
† Adjusted for age, gender, BMI, HbA_1c, U-ALB Ratio, U-Col4 Ratio, Hypertension, Hyperlipidemia, Alcohol intake and Smoking habit.
‡ Abbreviations are: CI, confidence interval; BMI, body mass index; HbA1c, glycated hemoglobin; U-ALB Ratio, urinary albumin-creatinine ratio; U-Col4 Ratio, urinary type4 collagen creatinine ratio.

ISSN: 1471-2369