The relation of C - reactive protein to chronic kidney disease in African Americans: the Jackson Heart Study

BMC Nephrology

Table 1 Characteristics of Study Participants in the Lower 75th and Upper 25^th percentile of C-Reactive Protein Stratified by Age 60 years

	Overall		Age < 60 years		Age ≥ 60 years
	L75^thP CRP (< 5.7 mg/L) n = 3254	U25^thP CRP (≥ 5.7 mg/L) n = 1066	L75^thP CRP (< 5.7 mg/L) n = 2071	U25^thP CRP (≥ 5.7 mg/L) n = 663	L75^thP CRP (< 5.7 mg/L) n = 1183	U25^thP CRP (≥ 5.7 mg/L) n = 403
C-reactive protein mg/L	2.1 ± 1.5	14.4 ± 15.2	2.0 ± 1.5	14.1 ± 10.6	2.2 ± 1.5	14.9 ± 20.6
*Demographic factors*
Age, years	54 ± 13	54 ± 12	46 ± 9	47 ± 8	67 ± 6	67 ± 6
Male, %	42.01	18.57	45.3	18.4	36.3	18.9
*Cardiovascular risk factors*
Body mass index, kg/m²	30.3 ± 6.1	36.1 ± 8.3	30.4 ± 6.3	37.4 ± 8.3	30.1 ± 5.8	34.0 ± 7.8
Systolic blood pressure, mmHg	127 ± 18	127 ± 18	123 ± 16	124 ± 16	134 ± 20	133 ± 20
Diastolic blood pressure, mmHg	80 ± 10	78 ± 10	81 ± 10	80 ± 10	78 ± 10	75 ± 11
Hypertension, %	57.6	69.0	46.3	57.6	77.4	87.6
Diabetes, %	13.7	18.9	9.8	15.5	20.6	24.3
Total/HDL cholesterol, ratio	4.1 ± 1.3	4.1 ± 1.4	4.2 ± 1.4	4.1 ± 1.5	4.0 ± 1.2	4.1 ± 1.3
Triglyceride, mg/dL	104 ± 76	113 ± 80	102 ± 83	109 ± 69	107 ± 63	119 ± 95
Current smoker, %	12.2	14.4	14.3	15.9	8.7	12.0
Anti-hypertension therapy, %	46.8	60.1	34.3	48.9	68.6	78.5
Lipid lowering therapy, %	12.0	10.5	6.8	7.8	21.1	14.9
HRT use in women, %	11.2	24.1	10.6	22.9	12.1	26.0
*Nutritional factors*
Total protein	79 ± 47	77 ± 48	86 ± 51	86 ± 53	66 ± 35	64 ± 35
*Kidney disease factors*
Chronic kidney disease, %	4.2	8.4	1.5	4.2	8.9	15.4

Values are % or mean ± standard deviation
HRT, hormone replacement therapy, L75th = lower 75^th percentile, U25 = upper 25^th percentile
Chronic kidney disease is defined as a glomerular filtraction rate, 60 ml/min/1.73 m²

ISSN: 1471-2369