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Table 2 Association of C-Reactive Protein with Chronic Kidney Disease (ml/min/1.73 m2) in the Pooled Study Population and Stratified by Sex

From: The relation of C - reactive protein to chronic kidney disease in African Americans: the Jackson Heart Study

 

CKD (eGFR < 60)

No CKD (eGFR ≥ 60)

p-value

Pooled**

   

N

228

4092

 
 

CRP (Geometric Mean ± SE)

CRP (Geometric Mean ± SE)

 

Adjustment

   

   Age and Sex

3.4 ± 1.1 mg/L

2.4 ± 1.0 mg/L

< 0.0001

   Multivariable*

3.2 ± 1.1 mg/L

2.4 ± 1.0 mg/L

< 0.0001

Women

   

N

178

2577

 
 

CRP (Geometric Mean ± SE)

CRP (Geometric Mean ± SE)

 

Adjustment

   

   Age

3.9 ± 1.1 mg/L

3.0 ± 1.0 mg/L

0.016

   Multivariable*†

3.7 ± 1.1 mg/L

3.1 ± 1.0 mg/L

< 0.0001

Men

   

N

50

1515

 
 

CRP (Geometric Mean ± SE)

CRP (Geometric Mean ± SE)

 

Adjustment

   

   Age

3.4 ± 1.2 mg/L

1.58 ± 1.0 mg/L

< 0.0001

   Multivariable*†

3.1 ± 1.2 mg/L

1.58 ± 1.0 mg/L

< 0.0001

  1. * adjusted for age, sex, body mass index, systolic and diastolic blood pressures, diabetes, current smoking status, hypertension drugs, lipid lowering drugs, hormone therapy replacement, triglycerides, total cholesterol/HDL ratio, and prevalent cardiovascular disease events.
  2. ** pooled signify both men and women included in the analysis
  3. † sex is excluded from list of covariates since analysis is stratified by sex
  4. CKD, Chronic kidney disease; eGFR, estimated glomerular filtration rate; CRP, C-reactive protein
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BMC Nephrology

ISSN: 1471-2369

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