Randomised Controlled Trial to determine the appropriate time to initiate peritoneal dialysis after insertion of catheter to minimise complications (Timely PD study)

Table 1 Explanation of definitions to be used as part of this study

Terms	Definitions
Dialysate leak [17]	Exit-Site leak: Appearance of any moisture around the PD catheter that can be identified as dialysate (leak that contains a high glucose concentration, documented by a positive glucose dipstick of the leaking fluid)
	Dialysate leaks include not only those occurring around catheter but also dialysate loss from the peritoneal cavity, except that via the lumen of the PD catheter. If the diagnosis is uncertain Tenckhoffogram (intraperitoneal infusion of contrast material through the catheter with computed tomography) performed to confirm the anatomical leak[18]
Peritonitis [19]	Presence of two clinical signs and symptoms:
	• abdominal pain, nausea, vomiting, diarrhoea, fever and cloudy dialysate
	• Peritoneal dialysate WCC > 100/mm³ with 50% neutrophils
	• Demonstration of bacteria on gram stain or culture
Exit site Infection (ESI)	Presence of purulent discharge or two of three of the following: erythema of >13 mm, induration and tenderness. Exit- site swab will be obtained in all suspected cases of ESI.
Tunnel Infection	Presence of two of three of the following: induration, tenderness, and radiographic evidence of a collection along the PD catheter tunnel.

ISSN: 1471-2369