From: Interventions for renal vasculitis in adults. A systematic review
Study ID | Inclusion criteria | Exclusion criteria |
---|---|---|
Adu 1997 | Patients 15-70 y with new-onset systemic necrotizing vasculitis. Wegener's granulomatosis, classical polyarteritis nodosa and microscopic polyarteritis diagnosed by histological or radiological evidence. | Â |
De Groot 2009a | newly diagnosed Wegener's Granulomatosis, microscopic polyangiitis, or renal-limited microscopic polyangiitis renal involvement: at least one of: serum creatinine >150 umol/l and <500 μmol/l, biopsy evidence of necrotizing GN, erythrocyte casts, or haematuria and proteinuria, confirmatory histology or ANCA positivity | Other multi-system autoimmune disease; hepatitis B or C virus or HIV infection/Serum creatinine > 500 μmol/l; previous cancer; pregnancy; age under 18 yrs or older than 80 yrs. |
Guillevin 1997 | Age > 15 years New diagnosis of systemic WG diagnosed clinically based on the presence of multi-organ involvement. Mono-visceral involvement representing a potential risk or severe morbidity of fatality. Histopathologic characterization of necrotizing granulomatosis vasculitis or evidence of either granulomatous inflammation and vasculitis or segmental necrotizing GN | NS |
Haubitz 1998 | New diagnoses of WG and MPA and renal involvement. Biopsy performed | Age < 18 y, pregnancy, HIV, malignancy, SCr > 200 μmol/L more than 1 year before presentation, cytotoxic drug therapy for > 1 week before start of study, HD for > 10 days before start of study. |