Figure 2From: Study Protocol: A Pilot Study to Determine the Safety and Efficacy of Induction-Therapy, De Novo MPA and Delayed mTOR-Inhibition in Liver Transplant Recipients with Impaired Renal Function. PATRON-Study Statistical flow-chart. The flow chart shows the two-step model of the single-arm prospective trial. If there are more than 8 responders (patients that do not have steroid-resistant acute rejection within 30 days after transplantation.) after inclusion of 9 patients, there will be a second stepp with additional inclusion of 20 patients. If more than 27 patients do not show steroid resistant acute rejection, the proposed treatment regimen is promising.Back to article page