Figure 10
From: Bone Morphogenetic Protein (BMP)-7 expression is decreased in human hypertensive nephrosclerosis
BMP-7 decreases expression of TGF-β receptor type I. Expression of TGF-β receptor type I after stimulation with BMP-7 (1, 10, 100 ng/ml) detected by double immunofluorescence: quantification of cell staining intensity was given in grey values by the software AnalySIS. Expression rate is changed compared to unstimulated cells, concomitant with reduced staining intensity (100 ng/ml: p < 0.01). Original magnification: × 1000. Results were analysed by Student's t-test and are displayed as the % of unstimulated cells in the mean ± standard error.