Table 1 Baseline patient, donor, and transplant procedure characteristics.
Characteristics | Statin (N = 221) | Non-statin (N = 394) | All (N = 615) | p-value |
|---|---|---|---|---|
Baseline patient characteristics | Â | Â | Â | Â |
   Age at transplant (y; N = 615) * | 51 ± 12 | 48 ± 15 | 50 | 0.002 |
   Male (%; N = 614) | 62.4 | 63.3 | 63.0 | 0.82 |
   Race (N = 615) |  |  |  |  |
White (%) | 86.9 | 81.5 | 83.4 | 0.08 |
Other (%) | 13.1 | 18.5 | 16.6 | Â |
   Body Mass Index (kg/m2; N = 599) * | 26 ± 5 | 25 + 5 | 26 | 0.002 |
   Etiology of ESRD (%, N = 615) |  |  |  |  |
DM | 18.6 | 13.4 | 15.3 | 0.12 |
HTN | 21.7 | 17.3 | 18.9 | Â |
Other | 50.7 | 59.1 | 56.1 | Â |
Unknown | 9.0 | 10.1 | 9.8 | Â |
   Charlson Co-morbidity Index |  |  |  |  |
   Total score (N = 611) | 2.13 ± 1.81 | 2.04 ± 1.90 | 2.08 | 0.60 |
   Myocardial Infarction (%, N = 611) | 9.9 | 5.6 | 7.2 | 0.05 |
   Severe liver disease (%, N = 611) * | 1.8 | 3.3 | 2.8 | 0.27 |
   Previous Transplant (%, N = 615) | 17.2 | 23.3 | 21.1 | 0.07 |
   PRA (%; N = 590) | 8.1 ± 18.8 | 9.0 ± 20.0 | 8.7 | 0.62 |
   Liver function |  |  |  |  |
AST (U/L; N = 541) | 22 ± 11 | 22 ± 13 | 22 ± 12 | 0.95 |
ALT (U/L; N = 542) | 28 ± 19 | 28 ± 19 | 28 ± 19 | 0.95 |
Alkaline phosphatase (U/L; N = 540)* | 97 ± 50 | 118 ± 113 | 110 ± 94 | 0.02 |
Tbili (mg/dL; N = 539) | 0.5 ± 0.2 | 0.6 ± 0.4 | 0.6 ± 0.4 | 0.61 |
   HbsAg positive (%; N = 615) | 2.3 | 0.5 | 1.1 | 0.05 |
   Anti-HCV positive (%; N = 615) | 6.3 | 8.4 | 7.6 | 0.59 |
   CMV IgG positive (%; N = 612) * | 73.3 | 81.3 | 78.4 | 0.02 |
Total cholesterol (3 m) (mg/dL; N = 467) Triglycerides (mg/dL; N = 456) | 200 ± 47 220 ± 124 | 181 ± 42 181 ± 118 | 188 197 | < 0.001 < 0.001 |
   Creatinine at 3 mos (mg/dL; N = 590)* | 1.8 ± 0.7 | 1.8 ± 1.1 | 1.8 | 0.28 |
Diabetes with complications (N = 611) | 21.3 | 14.4 | 16.9 | 0.03 |
Donor characteristics | Statin (N = 163) | Non-statin (N = 552) | All (N = 715) | p-value |
   Deceased donor (%; N = 615)* | 73.3 | 75.9 | 75.0 | 0.47 |
   Age (y; N = 594) | 37 ± 17 | 37 ± 17 | 37 ± 17 | 0.88 |
A Antigen Mismatch (%0 Antigen Mismatch, N = 597) | 35.6 | 39.9 | 38.4 | 0.75 |
B Antigen Mismatch (%0 Antigen Mismatch, N = 601) | 29.5 | 36.5 | 33.9 | 0.12 |
DR Antigen Mismatch (%0 Antigen Mismatch, N = 597) | 25.3 | 27.6 | 26.8 | 0.56 |
Transplant procedure characteristics | Â | Â | Â | Â |
Cold Ischemia Time (min; N = 551)* | 1186 ± 745 | 1327 ± 746 | 1275 | 0.03 |
Delayed graft function (%; N = 615) | 19.9 | 22.3 | 21.5 | 0.48 |
Induction protocol (%, N = 615)* | 26.2 | 25.1 | 25.5 | 0.76 |