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Table 2 Univariate and Multivariate Associations with MCV > 102 fl

From: Macrocytosis may be associated with mortality in chronic hemodialysis patients: a prospective study

 

Univariate (OR [95% CI])

P

Multivariate (OR [95% CI])

P

Malignancy*

3.86 [1.59, 9.38]

0.003

2.12 [0.73, 6.17]

0.168

Darbepoetin alfa to Hb ratio

1.15 [1.04, 1.27]

0.005

1.19 [1.07, 1.32]

0.001

Charlson-Age Comorbidity Index

1.18 [1.04, 1.33]

0.012

1.23 [1.07, 1.40]

0.003

Transferrin saturation

1.04 [1.01, 1.07]

0.013

---

 

Age 60 and above

3.34 [1.42, 7.86]

0.006

---

 

Antiepileptic medication

10.15 [1.10, 93.51]

0.041

---

 

Mean hemoglobin (g/L)

0.96 [0.93, 1.00]

0.025

---

 

Weekly darbepoetin alfa dose (mcg)

1.01 [1.00, 1.02]

0.033

---

 

Weekly weight adjusted darbepoetin alfa dose (mcg/kg)

3.21 [1.29, 7.98]

0.012

---

 
  1. * Hematologic and non-hematologic
  2. Variables included in the multivariate binary regression analysis: Malignancy, Darbepoetin alfa to Hb ratio and the Charlson-Age Comorbidity Index.