Uromodulin concentrations are not associated with incident CKD among persons with coronary artery disease

BMC Nephrology

Table 1 Characteristics of Participants in the Heart and Soul Cohort by Genotype

Characteristics	G/G (n = 683)	G/T (n = 172)	T/T (n = 24)	P value	P Value TT vs. Other
Whites
N	373	133	21	-	-
Age	68 ± 11	69 ± 10	64 ± 12	0.24	0.20
Male	86%	86%	86%	0.99	0.58
Body Mass Index	29 ± 5	29 ± 6	30 ± 6	0.48	0.23
Hypertension	66%	65%	81%	0.35	0.11
Diabetes	23%	15%	14%	0.11	0.34
Albumin-creatinine ratio (median, IQR)	10 (7-18)	8 (6-12)	9 (7-20)	0.23	0.86
Baseline Kidney Function
Creatinine Clearance (mean)	92 ± 36	93 ± 34	103 ± 40	0.28	0.12
eGFR (cysC) (mean)	69 ± 22	69 ± 21	79 ± 25	0.20	0.08
eGFR (Scr) (mean)	73 ± 20	74 ± 19	78 ± 22	0.51	0.38
Non-Whites
N	310	39	3	-	-
Age	65 ± 11	64 ± 9	57 ± 7	0.27	0.13
Male	77%	82%	33%	0.14	0.13
Body Mass Index	28 ± 6	29 ± 5	38 ± 8	0.02	0.02
Hypertension	78%	77%	100%	0.65	0.47
Diabetes	36%	31%	33%	0.82	0.71
Albumin-creatinine ratio (median, IQR)	11 (7-36)	11 (6-16)	49 (20-78)	0.35	0.15
Baseline Kidney Function
Creatinine Clearance (mean)	90 ± 37	92 ± 40	105 ± 26	0.66	0.39
eGFR (cysC) (mean)	72 ± 25	75 ± 22	72 ± 21	0.83	0.84
eGFR (Scr) (mean)	76 ± 27	82 ± 24	71 ± 10	0.29	0.59

P values are obtained using Kruskal-Wallis rank or the Mann-Whitney test for continuous variables, Fisher's exact test or Chi-square test for categorical variables.

ISSN: 1471-2369