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Table 1 Distribution of HLA-DQB1, -DQA1 and DPB1 alleles in patients with anti-GBM disease and normal controls

From: The association of HLA-DQB1, -DQA1 and -DPB1 alleles with anti- glomerular basement membrane (GBM) disease in Chinese patients

HLA alleles Anti-GBM disease
n × 2 = 88
Normal controls
n × 2 = 400
p pc OR 95% CI HLA alleles Anti-GBM disease
n × 2 = 88
Normal controls
n × 2 = 400
p pc OR 95% CI
DQB1*0201 17 95 0.37   0.77 0.43-1.37 DPB1*0801 3 1 0.02 1.76 14.08 1.45-137.03
DQB1*0301 15 45 0.13   1.62 0.86-3.06 DPB1*0901 4 3 0.022 1.94 6.3 1.39-28.68
DQB1*0302 2 13 1   0.69 0.15-3.12 DPB1*1101 0 1 1    
DQB1*0303 7 39 0.6   0.8 0.35-1.85 DPB1*1301 4 5 0.06   3.76 0.99-14.31
DQB1*0401 2 8 0.7   1.14 0.24-5.46 DPB1*1302 0 1 1    
DQB1*0501 13 45 0.36   1.37 0.70-2.66 DPB1*1601 1 4 1   1.14 0.13-10.31
DQB1*0502 3 24 0.44   0.55 0.16-1.88 DPB1*1602 0 1 1    
DQB1*0503 8 37 0.96   0.98 0.44-2.19 DPB1*1701 0 3 1    
DQB1*0602 21 94 0.94   1.02 0.59-1.75 DPB1*1801 1 7 1   0.65 0.078-5.31
DQA1*0101 1 17 0.22   0.26 0.034-1.97 DPB1*2001 2 4 0.3   2.3 0.42-12.77
DQA1*0102 19 148 0.006 0.53 0.47 0.27-0.81 DPB1*2002 0 2 1    
DQA1*0103 2 12 1   0.75 0.17-3.42 DPB1*2101 0 1 1    
DQA1*0201 16 36 0.011 0.97 2.25 1.18-4.27 DPB1*2301 0 3 1    
DQA1*0301 26 92 0.19   1.4 0.84-2.35 DPB1*2401 0 3 1    
DQA1*0302 3 3 0.075   4.67 0.93-23.54 DPB1*2402 3 5 0.16   2.79 0.65-11.89
DQA1*0401 1 12 0.48   0.37 0.048-2.90 DPB1*2601 3 4 0.11   3.49 0.77-15.90
DQA1*0501 19 70 0.37   1.3 0.73-2.29 DPB1*3301 13 44 0.32   1.4 0.72-2.73
DQA1*0601 1 10 0.7   0.45 0.057-3.55 DPB1*3501 0 3 1    
DPB1*0101 1 6 1   0.76 0.090-6.35 DPB1*4001 1 0 0.18    
DPB1*0201 24 98 0.59   1.16 0.69-1.95 DPB1*4501 0 3 1    
DPB1*0301 8 29 0.56   1.28 0.56-2.90 DPB1*4801 0 1 1    
DPB1*0302 1 3 0.55   1.52 1.16-14.80 DPB1*5201 0 1 1    
DPB1*0401 3 74 4.4 × 10-4 0.039 0.16 0.048-0.51 DPB1*5401 0 1 1    
DPB1*0402 15 82 0.46   0.8 0.44-1.46 DPB1*5701 0 2 1    
DPB1*0601 1 2 0.45   2.29 2.21-25.51 DPB1*6601 0 1 1    
DPB1*0602 0 1 1     DPB1*8601 0 1 1    
  1. [Abbreviations] pc, P corrected; OR, odds ratio; CI, confident interval.