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Table 2 Clinical and pathological characteristics of patients with anti-GBM disease, categorized by the presence of HLA gene

From: The association of HLA-DQB1, -DQA1 and -DPB1 alleles with anti- glomerular basement membrane (GBM) disease in Chinese patients

  DPB1*0401  
  positive negative p value
Gender (male/female) 1/2 29/12 0.23
Age (transformed by log10), mean ± standard deviation 1.37 ± 0.05 1.50 ± 0.19 0.011
Level of anti-GBM antibodies (%), mean ± standard deviation 71.53 ± 61.58 81.43 ± 46.63 0.73
Hemoptysis 3/3 13/41 0.042
Oliguria or anuria 1/3 16/41 1.00
Interval between onset and diagnosis (days), mean ± standard deviation 68.33 ± 31.34 62.87 ± 52.83 0.86
Scr (μmol/L), mean ± standard deviation 1024.33 ± 362.41 746.49 ± 387.91 0.24
Percentage of crescents in glomeruli, median (1st and 3rd quartile) 100 (87.5, 100) 94.87 (67.69, 100) 0.45
Dialysis-dependent or died 3/3 31/37 1.00
  1. [Abbreviations] Scr: serum creatinine.