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Table 2 Clinical and pathological characteristics of patients with anti-GBM disease, categorized by the presence of HLA gene

From: The association of HLA-DQB1, -DQA1 and -DPB1 alleles with anti- glomerular basement membrane (GBM) disease in Chinese patients

 

DPB1*0401

 
 

positive

negative

p value

Gender (male/female)

1/2

29/12

0.23

Age (transformed by log10), mean ± standard deviation

1.37 ± 0.05

1.50 ± 0.19

0.011

Level of anti-GBM antibodies (%), mean ± standard deviation

71.53 ± 61.58

81.43 ± 46.63

0.73

Hemoptysis

3/3

13/41

0.042

Oliguria or anuria

1/3

16/41

1.00

Interval between onset and diagnosis (days), mean ± standard deviation

68.33 ± 31.34

62.87 ± 52.83

0.86

Scr (μmol/L), mean ± standard deviation

1024.33 ± 362.41

746.49 ± 387.91

0.24

Percentage of crescents in glomeruli, median (1st and 3rd quartile)

100 (87.5, 100)

94.87 (67.69, 100)

0.45

Dialysis-dependent or died

3/3

31/37

1.00

  1. [Abbreviations] Scr: serum creatinine.