The ratio of CRP to prealbumin levels predict mortality in patients with hospital-acquired acute kidney injury

BMC Nephrology

Table 3 Multivariate Cox regression analysis for the selected possible predictors of mortality in patients with AKI

	CRP (mg/L)		prealbumin (mg/dL)		CRP/prealbumin		albumin (g/dL)		CRP/albumin		cholesterol (mg/dL)		CRP/cholesterol
	HR	p	HR	p	HR	p	HR	p	HR	p	HR	p	HR	p
unadjusted	1.108	0.006	1.404	0.002	1.057	0.000	1.185	0.075	1.128	0.022	1.154	0.043	1.039	0.001
model 1	1.123	0.003	1.398	0.002	1.059	0.000	1.185	0.083	1.137	0.017	1.166	0.041	1.043	0.001
model 2	1.121	0.005	1.404	0.002	1.058	0.000	1.166	0.121	1.132	0.027	1.171	0.034	1.043	0.001
model 3	1.052	0.285	1.100	0.407	1.037	0.023	0.974	0.785	1.029	0.653	0.947	0.453	0.993	0.633
model 4	1.051	0.320	1.099	0.414	1.037	0.027	0.967	0.737	1.027	0.681	0.949	0.470	0.991	0.588

The Hazard ratio (HR) for death was expressed per a 2 mg/dL increase in CRP, 5 mg/dL decrease in prealbumin, 0.5 g/dL decrease in albumin, 3 mg/dL decrease in cholesterol, 0.1 increase in CRP (mg/dL)/prealbumin (mg/dL), 1 increase in CRP (mg/dL)/albumin (g/dL), 0.1 increase in CRP (mg/dL)/cholesterol (mg/dL) for a univariate model and sequential adjustment models.
The multivariate analysis sequentially adjusted models for covariates as follows: Model 1, adjusted for age, gender; Model 2, adjusted for age, gender and sepsis; Model 3, adjusted for age, gender and SOFA; Model 4, adjusted for age, gender, sepsis and SOFA.

ISSN: 1471-2369