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Table 1 Main clinical data and comorbidities at diagnosis

From: Positron emission tomography in the diagnostic pathway for intracystic infection in adpkd and "cystic" kidneys. a case series

Case

Sex

Age (yrs)

GFR (mL/min)

CKD

stage

CRP mg/dL (normal < 0.5)

Fever

(max)

Microbiological

isolates

Cystic disease

Comorbidities-notes

1

F

60

On dialysis

V

Max 12 mg/dL

Max 38°C relapsing; often after dialysis

None

ADPKD, large liver and kidney cysts

Left nephrectomy for transplant wait listing 3 years previously

2

M

77

25

IV

Max 10 mg/dL

Max 38°C

None

Multiple kidney cysts, hypertensive nephrosclerosis

Severe cardiovascular disease, right nephrectomy for neoplasia 15 years previously

3

F

68

101

I

Max 2.4 mg/dL

Low-grade

E Coli (urine)

ADPKD, liver and kidney cysts

Previous cerebellar haemorrhage

4

M

83

18

IV

Max 5.5 mg/dL

Low-grade

E Coli (urine)

ADPKD, large liver and kidney cysts

Severe cardiovascular disease; blindness

5

F

55

40

III

Max 1.2 mg/dL

No

Frequent UTI (E Coli in the last episodes)

ADPKD, large liver and kidney cysts

Anxiety-depression, Child A cirrhosis; breast neoplasia

6

F

81

35 at hospitalization; 65 after therapy

IV - II

Max 36 mg/dL

Max 39.5°C

E Coli (urine)

Two large kidney cysts

Previous TIA, moderate hypertension

7

F

65

35

III

Max 0.8 mg/dL

Occasional low-grade

none

ADPKD, liver and kidney cysts

Anxiety-depression

8

M

71

70

II

Max 22 mg/dL

Max 40°C

Proteus Mirabilis (urine) 2 weeks before hospitalization

Multiple kidney cysts

GFR decrease to 35 mL/min on therapy with aminoglycosides

9

F

63

55

III

Max 1.0 mg/dL

No

Frequent UTI (E Coli, last one one month previously)

Acquired cystic disease

Kidney transplant recipient

10

F

68

24

IV

Max 13.7 mg/dL

Max 38°C

Frequent UTI; last episode 2 weeks previously (self treated)

ADPKD, large kidney cysts, few liver cysts

Hypertension, hyperparathyroidism

  1. Legend: F: female, M: male; GFR: glomerular filtration rate (Cockcroft formula or 24 hours urine collection); CRP: C-Reactive Protein; ADPKD: Autosomic dominant polycystic kidney disease. UTI: Urinary tract infections