Table 3 Blood pressure, proteinuria and use of anti hypertensive agents:
Characteristics | Total (n = 1129) | CKD Stage 3 | CKD Stage 4 | Pvalue |
|---|---|---|---|---|
Hypertension (%) | 92.7 | 91.2 | 94.1 | 0.06 |
Systolic BP < 130 mm Hg (%) | 22.1 | 22.5 | 21.6 | 0.72 |
Diastolic BP < 80 mm Hg (%) | 51.4 | 46.4 | 55.9 | 0.001 |
% of patients with BP < 130/80 mm Hg | 17.4 | 19.4 | 16.3 | 0.18 |
% of patients with BP < 140/90 mm Hg | 40.8 | 45.9 | 37.7 | 0.007 |
Systolic BP (mm Hg; mean ± SD) | 141 ± 19 | 141 ± 19 | 142 ± 20 | 0.4 |
Diastolic BP (mm Hg; mean ± SD) | 76 ± 11 | 78 ± 10 | 75 ± 11 | 0.001 |
Percentage of pts with proteinuria (> 300 mg/24 hrs) (%) | 62.8 | 56.6 | 66.8 | 0.001 |
Proteinuria (g/24 h; mean [SD]) | 1.2 ± 1.8 | 1.2 ± 1.8 | 1.3 ± 1.8 | 0.60 |
Angiotensin-converting enzyme (ACE) inhibitors (%) | 43.3 | 46.9 | 40.0 | 0.02 |
Angiotensin II receptor blockers (ARB) (%) | 44.8 | 47.7 | 42.2 | 0.06 |
Combined ACE and ARB (%) | 10.8 | 12.1 | 9.6 | 0.18 |
Diuretics (%) | 65.7 | 61.5 | 69.6 | 0.004 |
Calcium channel blockers (%) | 45.7 | 45.8 | 45.6 | 0.94 |
Beta blockers (%) | 21.1 | 22.5 | 19.8 | 0.25 |
Alpha blockers (%) | 23.4 | 23.5 | 23.3 | 0.95 |
% of patients with 3 or more antihypertensive drugs | 47.7 | 45.8 | 49.7 | 0.18 |
Mean serum potassium levels (mEq/dL; mean ± SD, [range]) | 4.82 ± 0.60 [3-6.7] | 4.71 ± 0.57 [3-6.4] | 4.88 ± 0.61 [3.1-6.7] | 0.001 |
% of patients with potassium levels > 5.4 mEq/dL | 14.3 | 9.8 | 17.1 | 0.001 |