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Table 2 Characteristics at the initiation of hemodialysis of the 133 patients with and without cardiovascular events

From: Carotid artery calcification at the initiation of hemodialysis is a risk factor for cardiovascular events in patients with end-stage renal disease: a cohort study

Variables

CV events (+)

CV events (-)

p value

No. of patients

47 (35)

86 (65)

 

Age (y)

66.7 ± 9.4

63.4 ± 10.9

0.10

Male

29 (62)

48 (56)

0.51

Hypertension

46 (98)

79 (92)

0.13

Diabetes mellitus

30 (64)

46 (53)

0.25

Dyslipidemia

38 (81)

64 (74)

0.40

Smoking

26 (55)

33 (38)

0.06

Previous CV disease

21 (45)

31 (36)

0.33

Dose of ESA (U/week)

9000 (4500-9000)

9000 (9000-9000)

0.34

Statins

16 (34)

14 (16)

0.02

ACEI and/or ARB

24 (51)

41 (48)

0.71

SBP (mm Hg)

155 ± 15

156 ± 23

0.92

DBP (mm Hg)

78 ± 10

80 ± 10

0.34

Pulse pressure (mm Hg)

76 ± 12

75 ± 19

0.51

Body mass index (kg/m2)

20 (18-23)

21 (19-22)

0.43

Blood urea nitrogen (mg/dL)

92 (73-114)

90 (80-110)

0.60

Serum creatinine (mg/dL)

8.4 (6.9-9.7)

9.5 (8.3-10.9)

< 0.01

Hemoglobin (g/dL)

8.4 ± 1.1

8.1 ± 1.3

0.22

Up/Ucr

4.4 (2.0-7.2)

4.6 (1.8-8.1)

0.75

Serum albumin (g/dL)

3.1 ± 0.6

3.2 ± 0.6

0.43

Ca-P product (mg2/dL2)

51.5 (43.7-61.4)

53.3 (43.5-65.0)

0.58

C-reactive protein (mg/dL)

0.14 (0.05-0.44)

0.09 (0.04-0.28)

0.30

intact-PTH (pg/mL)

235 (150-302)

245 (160-381)

0.41

CCA-IMT (mm)

0.83 (0.73-0.97)

0.77 (0.64-0.95)

0.09

CAP

35 (74)

51 (59)

0.08

Calcified plaque

24 (51)

22 (26)

< 0.01

CAAC

41 (87)

53 (62)

< 0.01

AAC

28 (60)

44 (51)

0.35

Low ABI

10 (22)

11 (13)

0.18

Duration of follow-up (months)

19.2 (9.1-32.5)

51.6 (38.4-65.7)

< 0.01

  1. Values are expressed as the mean ± SD, number (%), or median (interquartile range). Abbreviations: CV, cardiovascular; ESA, erythropoiesis-stimulating agents; ACEI, angiotensin-converting enzyme inhibitors; ARB, angiotensin II receptor blockers; SBP, systolic blood pressure; DBP, diastolic blood pressure; Up/Ucr, urinary protein-creatinine ratio; Ca-P, calcium-phosphorus; PTH, parathyroid hormone; CCA-IMT, common carotid artery-intima-media thickness; CAP carotid artery plaque; CAAC, carotid artery calcification; AAC, aortic arch calcification; ABI, ankle-brachial index.