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Table 4 Results of studied groups: antioxidants and lipid peroxidation biomarker.

From: The relationships between exogenous and endogenous antioxidants with the lipid profile and oxidative damage in hemodialysis patients

Biomarkers

Healthy Subjects (n = 20)

Hemodialysis Patients (n = 29)

 

Men (n = 10)

Women (n = 10)

Men (n = 19)

Women (n = 10)

GSH (μmol.g/Hb)

6.03 ± 0.26

7.87 ± 0.27a

 

5.6 ± 0.2

6.5 ± 0.4

7.8 ± 0.4

7.9 ± 0.4

CAT (K/mg Hb)

27.96 ± 4.18

56.99 ± 4.25a

 

26.6 ± 6.9

29.3 ± 5.2

55.5 ± 5.5

61.1 ± 7.5

GPx

11.57 ± 0.39

6.61 ± 0.21a

(μmol NADPH.min/g Hb)

12.2 ± 0.5

11.0 ± 0.5

6.5 ± 0.3

7.0 ± 0.3

SOD (U SOD/mg Hb)

0.69 ± 0.49

0.91 ± 0.03a

 

0.6 ± 0.04

0.8 ± 0.07

0.9 ± 0.05

0.9 ± 0.05

MDA (μmol/L)

4.53 ± 0.16

6.92 ± 0.36a

 

4.3 ± 0.2

4.8 ± 0.3

7.4 ± 0.6

6.1 ± 0.2

  1. The values represent the mean ± standard error of the mean (SEM).
  2. a p < 0.05 when compared with healthy subjects.
  3. Abbreviations: GSH: reduced glutathione; CAT: catalase activity; GPX: glutathione peroxidase activity;
  4. SOD: superoxide dismutase activity; MDA: malondialdehyde.
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BMC Nephrology

ISSN: 1471-2369

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