Figure 1
Effect of ozonated autohemotherapy on renal function after Isc and Isc/R. The rats received an intrafemoral injection of their blood driven from caudal vein and treated with O2 or a mixture of O2/O3; the injection was performed 30 min before Isc or at the induction of post-Isc R. Serum creatinine and blood urea nitrogen levels were measured. Isc and Isc/R rats subjected to O2/O3 autohemotherapy showed significant reductions of serum creatinine and blood urea nitrogen levels as compared with animals subjected to O2 autohemotherapy. Abbreviations: C = controls rats, Sham = sham-operated rats, Isc = rats submitted to 60 min of ischemia by clamping the renal artery; Isc/R = rats submitted to 60 min of ischemia followed by 60 min reperfusion. *p < 0.05