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Table 3 Median adipokine levels among participants treated with high-dose and usual-dose ESA and unadjusted and adjusted odds of adipokine being below the median

From: Association between high-dose erythropoiesis-stimulating agents, inflammatory biomarkers, and soluble erythropoietin receptors

Variable High-dose ESA
(≥1 mcg/kg/wk of
darbepoetin-α)
(n = 11)
Usual-Dose ESA
(< 1 mcg/kg/wk of
darbepoetin-α)
(n = 21)
Unadjusted Odds Ratio, *
(5-95% CI)
p-value
Adjusted Odds Ratio, * (5-95% CI)
p-value
Adiponectin (ng/ml) 18718.6 (13328.6, 33469.4) 15397.4 (8032.5, 53063.7) 0.76 (0.2-3.3)
p = 0.7
7.8 (0.5-109.2)
p = 0.1
Leptin (ng/ml) 30.9 (1.5, 102.6) 43.4 (9.8, 82.6) 2.33 (0.5-10.5)
p = 0.3
1.7 (0.1-19.2)
p = 0.7
  1. *Odds of cytokine being below the median among those in high vs usual dose ESA,
  2. **Adjusted for gender, hemoglobin, and weight