Skip to main content

Advertisement

Table 3 Time weighted analysis in VDRA + −group

From: Effect of vitamin-D analogue on albuminuria in patients with non-dialysed chronic kidney disease stage 4–5: a retrospective single center study

  Before After P
Kidney Function
eGFR (ml/min) 14.8 ± 3.6 12.6 ± 5.5 <0.001
Delta eGFR (ml/min/day) −0.018 ± 0.032 −0.013 ± 0.020 Ns
U-Albumin (g/d) 1.75 ± 1.64 1.60 ± 1.48 =0.05
Mineral-Bone
S-calcium (mmol/l) 1.15 ± 0.06 1.15 ± 0.07 Ns
S-phosphate (mmol/l) 1.51 ± 0.28 1.62 ± 0.38 Ns
S-PTH (pmol/l) 26.7 ± 11.5 23.8 ± 11.2 Ns
Blood Pressure
Systolic (mmHg) 147 ± 19 147 ± 17 Ns
Diastolic (mmHg) 82 ± 9 84 ± 10 Ns
  1. Time average values of all 24 h urinary collections before and after starting treatment with alfacalcidol in 59 patients with CKD 4–5. Number of urinary collections varied from 1 to 4 before and from 1 to 6 after. The mean time follow up time was 422 days (range 66–1347) before start of alfacalcidol and 364 (72–1196) after. Mean ± SD.