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Table 2 Health screening results categorized by HbA1c: KEEP database (2008–2009)

From: Dysglycemia but not lipids is associated with abnormal urinary albumin excretion in diabetic kidney disease: a report from the Kidney Early Evaluation Program (KEEP)

   Quartiles of Glycosylated Hemoglobin (HbA1c) Compare Q1 & Q4 (pvalue) §
  All, n Q1 Q2 Q3 Q4  
   [4.5 to 6.2] [6.3 to 6.9] [7.0 to 8.1] [8.2 to 18.0]  
n(row percentage) 2141 (100) 576 (26.9) 564 (26.3) 482 (22.5) 519 (24.2)  
SBP (mm of Hg) ‡ 138 (124–150) 136 (123–149) 137 (123–151) 138 (124–149) 139 (128–151) 0.0942
DBP (mm of Hg) ‡ 78 (70–86) 78 (70–85) 75 (68–84) 78 (70–86) 80 (72–89) 0.0001
PP (mm of Hg) ‡ 59 (48–70) 58 (48–70) 60 (48.5-71) 60 (49–70) 58 (49–69) 0.3544
BMI (kg/m2)‡ 31.2 (27.4-36.6) 29.8 (26.3-34.9) 31.1 (27.3-36.3) 31.6 (27.7-36.8) 33.2 (28.7-38.3) <.0001
WC (cm)‡ 42 (38–46) 41 (37–45) 42 (38–46) 42 (39–47) 44 (39–48) <.0001
Serum creatinine 1.13 (0.95-1.34) 1.15 (0.99-1.37) 1.16 (0.99-1.37) 1.17 (0.96-1.36) 1.03 (0.85-1.28) <.0001
Estimated GFR 55.4 (46.1-68.9) 54.4 (44.7-59.8) 53.0 (44.6-59.5) 54.8 (45.9-65.3) 63.0 (50.4-84.4) <.0001
Serum TC (mg/dl) ‡ 177 (150–207) 178.5 (151.5-201.5) 170.0 (146.5-199.0) 171.0 (146.0-203.0) 188.0 (159.0-226.0) <.0001
Serum LDL (mg/dl) ‡ 89.5 (67–114) 90.5 (69–113) 84 (64–109) 86 (66–110) 98 (73–128) 0.0002
Serum HDL (mg/dl) ‡ 47 (38–57) 50 (41–61.5) 48 (39–57) 45 (38–54) 44 (37–55) <.0001
Serum TG (mg/dl) ‡ 170 (117–250) 150 (108.5-214.5) 164.5 (113–241) 169 (114–253) 201 (142–301) <.0001
Urinary ACR (mg/g)       <.0001
   < 30 1048 (49.0) 342 (59.4) 329 (58.3) 246 (51.0) 131 (25.2)  
   30 -300 966 (45.1) 210 (36.5) 214 (37.9) 205 (42.5) 337 (64.9)  
   > 300 127 (5.9) 24 (4.2) 21 (3.7) 31 (6.4) 51 (9.8)  
Serum Calcium (mg/dl) ‡ 9.7 (9.4-10) 9.7 (9.4-10.0) 9.7 (9.4-10.0) 9.6 (9.3-9.9) 9.6 (9.3-9.9) 0.4078
Serum Phosphorus (mg/dl)‡ 3.6 (3.2-4) 3.6 (3.2-4.0) 3.6 (3.2-4.0) 3.6 (3.2-3.9) 3.65 (3.2-4.0) 0.4301
Hemoglobin (g/dl) ‡ 13.3 (12.2-14.3) 13.2 (12.1-14.3) 13.1 (12.1-14.0) 13.3 (12.2-14.4) 13.7 (12.4-14.7) <.0001
  1. Note: Values are n (column percent) unless otherwise indicated.
  2. Abbreviations: HbA1c, Glycosylated Hemoglobin; KEEP, Kidney Early Evaluation Program; SBP, Systolic Blood Pressure; DBP, Diastolic Blood Pressure; PP, Pulse Pressure; BMI, Body Mass Index; WC, Waist Circumference; TC, Total Cholesterol; LDL, Low Density Lipoprotein; HDL, High Density Lipoprotein; TG, Triglyceride; ACR, Albumin-creatinine ratio.
  3. ‡ Median (IQR).
  4. § chi2 for categorical variables and t-test for continuous variables.