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Figure 1 | BMC Nephrology

Figure 1

From: Bone marrow-derived cells can acquire renal stem cells properties and ameliorate ischemia-reperfusion induced acute renal injury

Figure 1

Engraftment of BM derived cells into I/R-injured kidneys. (A) Confirmation of chimerism in mice transplanted with bone marrow from GFP mice. Representative peripheral blood from wild-type (WT) mice and chimeric BMT mice 5 weeks after BMT were analysised by FACS. CD45 expression in recipient mice was also evaluated at the same time point. (B) BM-derived GFP positive cells within recipient kidneys. No GFP+ cell was observed in WT mice, while donor derived GFP+ cells were widely infiltrated in saline-treated mice. G-CSF administration mobilized more BM-derived cells to the injured kidney compared to the saline-treated mice. Nuclei were stained with DAPI (blue). Scale bars = 50 μm.

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