Proteinuria and hypoalbuminemia are risk factors for thromboembolic events in patients with idiopathic membranous nephropathy: an observational study

Table 1 Patients with idiopathic membranous nephropathy with thromboembolic events*

	Age (y)	Sex	Year of diagnosis	Type of event, test (treatment)	Serum albumin (mg/dl), proteinuria (g/24 h)	Time to diagnosis (mth)
1	68	M	1995	PE, V/Q (Pred + CycloP)	1.8, 14	- 2
2	43	M	1998	PE, V/Q (Pred + CycloP)	1.7, 14	- 1
3	82	M	1999	IleofemDVT^#, US (spontaneous remission)	2.0, 12	+ 6
4	58	M	2000	PE, V/Q (Pred + CycloP)	1.9, 11	0
5	58	F	2001	RVT, US (Pred + CycloP)	2.1, 7	0
6	68	F	2002	PE, CTPA (Pred + CycloP)	2.2, 5	0
7	79	M	2002	PE^#, CTPA (Pred + MMF)	2.8, 9	+ 2
8	72	M	2003	CVA^# (Pred + MMF)	1.7, 14	+ 3
9	50	M	2003	DVT, US (Pred + CycloP)	1.5, 12	- 2
10	64	F	2004	DVT, US (Pred + CycloP)	2.2, 5	- 0.5
11	42	M	2005	PE, CTPA (spontaneous remission)	2.0, 12	0
12	22	M	2005	PE, CTPA (Pred + CsA)	1.2, 12	0
13	39	M	2005	PE^#, CTPA (Pred + CycloP)	1.9, 11	+ 1
14	61	M	2007	PE^#, CTPA (Pred + CycloP)	1.6, 12	+ 1

*14/15 had complete data sets.
PE, pulmonary embolism; V/Q, ventilation/perfusion; RVT, renal vein thrombosis; CTPA, computed tomographic pulmonary angiogram; CVA, cerebrovascular accident; DVT, deep vein thrombosis; Pred, prednisolone; CsA, ciclosporin; CycloP, cyclophosphamide; MMF, mycophenolate mofetil.
All the patients who presented with TEs (patient 1, 2, 4, 5, 6, 9 – 12; 64%) were immediately anticoagulated on confirmation of the diagnosis of TE.
^#Not on prophylactic anti-coagulation.

ISSN: 1471-2369