From: Association of pre-transplant statin use with delayed graft function in kidney transplant recipients
Characteristics | Statin | Non-statin | Total | p-value |
---|---|---|---|---|
 | N = 93 | N = 176 | N = 269 |  |
Recipient characteristics | Â | Â | Â | Â |
Age (years) | 53.7 ± 11.0 | 47.5 ± 13.5 | 49.7 ± 13.0 | <0.001 |
Male gender (%) | 62(67%) | 115(65%) | 177(66%) | 0.83 |
Race | Â | Â | Â | 0.06 |
 Caucasian | 81(87%) | 150(85%) | 231(86%) |  |
 Other | 12(13%) | 26(15%) | 38(14%) |  |
Body Mass Index1 (kg/m2) | Â | Â | Â | 0.08 |
 <18,5 | 1(1%) | 5(3%) | 6(2%) |  |
 18.5-24.9 | 33(37%) | 76(43%) | 109(41%) |  |
 25-29.9 | 32(35%) | 70(40%) | 102(38%) |  |
 >30 | 24(27%) | 25(14%) | 49(19%) |  |
Co-morbidities | Â | Â | Â | Â |
 Hypertension | 89(96%) | 148(84%) | 237(88%) | 0.005 |
 Coronary artery disease | 11(12%) | 12(7%) | 23(9%) | 0.16 |
 Peripheral vascular disease | 4(4%) | 5(3%) | 9(3%) | 0.53 |
 Cerebrovascular disease | 2(2%) | 2(1%) | 4(1%) | 0.51 |
 Chronic lung disease | 6(7%) | 12(7%) | 18(7%) | 0.91 |
 Diabetes mellitus | 9(10%) | 12(7%) | 21(8%) | 0.41 |
Smoker | Â | Â | Â | 0.78 |
 Current | 1(1%) | 1(1%) | 2(1%) |  |
 Former | 41(44%) | 84(48%) | 125(46%) |  |
 Never | 51(55%) | 91(51%) | 142(53%) |  |
Etiology of ESRD | Â | Â | Â | 0.18 |
 Polycystic kidney disease | 23(25%) | 30(17%) | 53(19%) |  |
 Glomerulonephritis | 14(15%) | 33(19%) | 47(17%) |  |
 Focal sclerosing | 4(4%) | 6(3%) | 10(4%) |  |
 Focal and segmental proliferative | 0(0%) | 9(5%) | 9(3%) |  |
 IgA nephropathy | 14(15%) | 29(16%) | 43(16%) |  |
 Reflux nephropathy | 8(9%) | 19(11%) | 27(10%) |  |
 Diabetic nephropathy | 7 (8%) | 4 (2%) | 11 (4%) |  |
 Other | 27(29%) | 61(35%) | 88(33%) |  |
Renal replacement therapy | Â | Â | Â | 0.55 |
 Haemodialysis | 56(60%) | 97(55%) | 153(57%) |  |
 Peritoneal dialysis | 27(29%) | 52(30%) | 79(29%) |  |
 None | 10(11%) | 27(15%) | 37(14%) |  |
Previous transplants | 15% | 9% | 11% | 0.10 |
Length of admission (days) | 8.6 ± 4.2 | 7.9 ± 3.8 | 8.2 ± 4.0 | 0.19 |
Donor characteristics | Â | Â | Â | Â |
Age at transplant (years) | 47.8 ± 14.6 | 44.0 ± 15.2 | 45.33 ± 13.02 | 0.05 |
Male gender (%) | 42(45%) | 83(47%) | 125(47%) | 0.76 |
Body Mass Index1 (kg/m2) | Â | Â | Â | 0.23 |
 <18.5 | 0(0%) | 8(5%) | 8(3%) |  |
 18.5-24.9 | 32(35%) | 57(33%) | 89(34%) |  |
 25-29.9 | 42(46%) | 76(43%) | 108(45%) |  |
 >30 | 17(19%) | 32(19%) | 49(18%) |  |
Co-morbidities | Â | Â | Â | Â |
 Hypertension | 14(15%) | 20(11%) | 34(13%) | 0.38 |
 Hypertension | 14(15%) | 20(11%) | 34(13%) | 0.38 |
 Diabetes | 2(2%) | 4(2%) | 6(2%) | 0.83 |
 Current | 23(25%) | 49(28%) | 72(27%) |  |
 Former | 21(22%) | 36(20%) | 56(21%) |  |
 Never | 49(53%) | 91(52%) | 140(52%) |  |
Donor type | Â | Â | Â | 0.35 |
 Donation after brain death | 49(53%) | 94(53%) | 143(53%) |  |
 Donation after cardiac death | 13(14%) | 15(9%) | 28(10%) |  |
 Life | 31(33%) | 67(38%) | 98(37%) |  |
Cause of death | 0.36 | Â | Â | Â |
 Subarachnoid haemorrhage | 22(36%) | 28(26%) | 50(29%) |  |
 Cardiac arrest | 6(10%) | 19(17%) | 25(15%) |  |
 Intracranial haemorrhage | 9(14%) | 15(14%) | 24(14%) |  |
 Cyclist | 6(10%) | 4(4%) | 10(6%) |  |
 Fall | 4(6%) | 5(4%) | 9(5%) |  |
 Traffic accident | 2(3%) | 5(4%) | 7(4%) |  |
 Hypoxia | 3(5%) | 4(4%) | 7(4%) |  |
 Other | 10(16%) | 29(27%) | 39(23%) |  |
Inotropic support | 52(84%) | 95(87%) | 147(86%) | 0.55 |
eGFR (mL/min/1.73 m2) | 90.8 ± 22.8 | 94.4 ± 25.0 | 93.2 ± 24.3 | 0.25 |
Transplant procedure characteristics | Â | Â | Â | Â |
Mismatch | 3(2–5) | 4(2–5) | 4(2–5) | 0.05 |
Cold ischaemic time (hours) | 8.2 ± 4.5 | 7.6 ± 4.5 | 7.7 ± 4.5 | 0.29 |
Warm ischaemic time (hours) | 0.6 ± 0.2 | 0.6 ± 0.2 | 0.6 ± 0.2 | 0.93 |