From: Mineral and bone disorder in Chinese dialysis patients: a multicenter study
Variables | All participants (n = 2074) | HD (n = 1711) | PD (n = 363) | P value |
---|---|---|---|---|
Age (years) | 57.5 ± 14.3 | 57.1 ± 14.2 | 59.0 ± 14.4 | 0.03 |
Male (%) | 53.8 | 55.8 | 44.1 | < 0.001 |
Duration of dialysis (months) | 33.6 ± 40.7 | 47.8 ± 41.2 | 24.1 ± 20.0 | < 0.001 |
Cause of ESRD (%) | ||||
Glomerulonephritis | 47.5 | 49.4 | 38.6 | < 0.001 |
Hypertension | 12.1 | 11.6 | 14.6 | 0.11 |
Diabetes | 11.2 | 8.9 | 22.0 | < 0.001 |
Interstitial nephritis | 7.4 | 7.6 | 6.3 | 0.44 |
Obstructive nephropathy | 2.4 | 2.4 | 2.5 | 0.85 |
Others | 19.4 | 20.1 | 16.0 | 0.18 |
Hemoglobin (g/L) | 101.0 ± 2.1 | 101.1 ± 2.0 | 99.3 ± 2.1 | 0.14 |
Serum albumin (mg/L) | 37.5 ± 5.0 | 37.8 ± 4.8 | 36.1 ± 5.7 | < 0.001 |
Corrected calcium (mg/dL) (%) | ||||
 Mean ± SD | 9.3 ± 1.1 | 9.3 ± 1.1 | 9.2 ± 1.1 | 0.03 |
 < 8.4 | 19.4 | 19.4 | 19.4 | 1.00 |
 8.4-9.5 | 39.6 | 38.6 | 44.0 | 0.07 |
 > 9.5 | 41.0 | 42.0 | 36.6 | 0.06 |
 Phosphorus binder prescription (%) | 70.5 | 71.4 | 66.7 | 0.35 |
 Vitamin D prescription (%) | 61.2 | 64.6 | 43.2 | < 0.001 |
Phosphorus (mg/dL) (%) | ||||
 Mean ± SD | 6.2 ± 2.1 | 6.3 ± 2.1 | 5.7 ± 2.0 | < 0.001 |
 < 3.5 | 5.8 | 5.0 | 9.6 | < 0.01 |
 3.5-5.5 | 38.5 | 37.6 | 43.0 | 0.06 |
 > 5.5 | 55.6 | 57.4 | 47.4 | < 0.01 |
 Phosphorus binder prescription (%) | 73.0 | 72.6 | 75.0 | 0.65 |
 Vitamin D prescription (%) | 66.6 | 66.5 | 67.5 | 0.85 |
iPTH (pg/mL) (%) | ||||
 Median (IQR) | 269.0 (132.0 - 472.9) | 265.0 (127.2 – 456.3) | 304.5 (162.0 – 486.7) | 0.03 |
 < 150 | 27.8 | 29.0 | 22.3 | < 0.01 |
 Vitamin D prescription (%) | 48.1 | 52.3 | 23.5 | < 0.001 |
 150-300 | 26.6 | 26.5 | 27.3 | 0.74 |
 Vitamin D prescription (%) | 67.9 | 72.4 | 49.5 | < 0.001 |
 > 300 | 45.5 | 44.5 | 50.4 | 0.05 |
 Vitamin D prescription (%) | 78.2 | 77.5 | 81.2 | 0.34 |
Phosphorus binder prescription (%) | 69.4 | 70.8 | 64.0 | 0.03 |
Vitamin D prescription (%) | 67.4 | 69.2 | 59.8 | < 0.01 |
Dialysate calcium (%) | ||||
1.25 mmol/L | 19.0 | 19.9 | 15.1 | 0.08 |
1.5 mmol/L | 58.2 | 68.7 | 12.8 | < 0.001 |
1.75 mmol/L | 22.8 | 11.4 | 72.1 | < 0.001 |
Elemental calcium (g/day) | 1.07 ± 0.65 | 1.11 ± 0.67 | 0.91 ± 0.52 | < 0.001 |
> 1.5 g/day (%) | 28.4 | 30.4 | 19.5 | < 0.01 |