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Table 1 Demographic characteristics of the study population

From: Postdialysis blood pressure rise predicts long-term outcomes in chronic hemodialysis patients: a four-year prospective observational cohort study

Factor

All

Patients with postdialytic SBP rise > 5 mmHg

Patients with postdialytic SBP change between -5 to 5 mmHg

Patients with postdialytic SBP drop > 5 mmHg

p Value

Patient number

115

39

27

49

 

Age (year)

64.0 ± 13.6

68.6 ± 11.5

65.1 ± 16.0

59.6 ± 12.6

0.007*

Male gender (%)

45.2

41.0

33.3

55.1

0.153

Dialysis duration (year)

5.8 ± 5.3

4.5 ± 5.3

6.8 ± 6.1

6.2 ± 4.7

0.180

Body mass index (Kg/m2)

22.0 ± 3.5

21.7 ± 3.4

21.9 ± 3.6

22.2 ± 3.5

0.840

Smoking index

0.46 ± 0.74

0.46 ± 0.79

0.41 ± 0.69

0.49 ± 0.74

0.900

Kt/V

1.60 ± 0.26

1.61 ± 0.22

1.62 ± 0.22

1.59 ± 0.31

0.873

Comorbidities (%)

     

   Diabetes mellitus (%)

40.0

43.6

37.0

38.8

0.844

   Hypertension (%)

91.3

89.7

92.6

91.8

1.000

   Cardiovascular disease (%)

26.1

30.8

29.6

20.4

0.487

   Prior stroke (%)

4.3

7.7

0.0

4.1

0.365

   Malignancy (%)

7.8

15.4

3.7

4.1

0.136

Medications

     

   ACE inhibitor/ARB (%)

47.0

53.8

44.4

42.9

0.565

   Antihypertensive agents (%)

79.1

89.7

85.2

67.3

0.025*

   Antiplatelet agents (%)

33.0

41.0

33.3

26.5

0.356

   Statins (%)

35.7

33.3

37.0

36.7

0.933

   Fibrates (%)

7.0

10.3

3.7

6.1

0.719

   Vitamin D3 (%)

19.1

15.4

18.5

22.4

0.702

Hepatitis B infection (%)

7.8

7.7

0.0

12.2

0.172

Hepatitis C infection (%)

18.3

12.8

25.9

18.4

0.409

Laboratory data

     

   Albumin (g/dL)

4.1 ± 0.3

4.1 ± 0.3

4.2 ± 0.3

4.2 ± 0.3

0.224

   Total cholesterol (mg/dL)

173.5 ± 36.1

175.4 ± 35.0

171.1 ± 31.4

173.4 ± 39.9

0.895

   Triglycerides (mg/dL)

182.9 ± 125.2

166.6 ± 113.1

190.8 ± 145.1

191.4 ± 123.9

0.614

   Sodium (mmol/L)

139.8 ± 2.9

139.4 ± 2.9

139.9 ± 3.5

140.0 ± 3.1

0.693

   Chloride (mmol/L)

99.7 ± 2.5

100.1 ± 2.3

100.0 ± 2.6

99.1 ± 2.6

0.148

   Bicarbonate (mmol/L)

24.0 ± 2.5

24.1 ± 2.5

23.7 ± 2.3

24.1 ± 2.6

0.770

   ALT (U/L)

20.4 ± 12.5

20.5 ± 12.1

23.0 ± 18.4

18.8 ± 8.0

0.460

   Alk-P (mg/dL)

113.9 ± 61.5

117.3 ± 79.3

103.0 ± 42.4

117.1 ± 54.2

0.578

   Fasting glucose (mg/dL)

139.7 ± 66.6

143.3 ± 57.0

140.2 ± 75.8

136.4 ± 69.6

0.890

   HbA1c (%)

6.2 ± 1.5

6.0 ± 1.1

6.0 ± 1.6

6.3 ± 1.8

0.573

   WBC count (1000 per cumm)

6.3 ± 1.8

6.2 ± 1.6

6.4 ± 1.6

6.5 ± 2.0

0.741

   Hemoglobin (g/dL)

10.1 ± 1.3

9.7 ± 1.0

10.2 ± 1.6

10.3 ± 1.4

0.077

   High-sensitive CRP (mg/dL)

0.514 ± 0.706

0.573 ± 0.662

0.343 ± 0.305

0.562 ± 0.875

0.357

   Ferritin (ng/mL)

510.3 ± 570.7

508.5 ± 541.1

595.1 ± 944.2

464.9 ± 229.4

0.723

   Transferrin saturation (%)

26.3 ± 11.7

24.8 ± 10.8

29.9 ± 15.7

25.4 ± 9.5

0.178

Peridialytic blood pressure

     

   predialytic SBP (mmHg)

143.1 ± 15.5

138.1 ± 16.6

141.5 ± 13.8

147.9 ± 14.3

0.009*

   postdialytic SBP (mmHg)

143.1 ± 17.1

152.6 ± 19.2

142.7 ± 14.5

135.7 ± 12.6

< 0.001*

   predialytic DBP (mmHg)

78.2 ± 6.8

74.9 ± 6.9

77.9 ± 5.8

81..0 ± 6.1

< 0.001*

   postdialytic DBP (mmHg)

79.1 ± 6.2

80.0 ± 6.8

79.6 ± 6.6

78.2 ± 5.4

0.345

   predialytic MAP (mmHg)

99.8 ± 9.1

96.0 ± 9.6

99.1 ± 7.7

103.3 ± 8.1

0.001*

   postdialytic MAP (mmHg)

100.5 ± 9.0

104.2 ± 10.1

100.6 ± 8.4

97.3 ± 7.2

0.001*

   predialytic PP (mmHg)

64.9 ± 11.4

63.2 ± 11.8

63.6 ± 11.1

67.0 ± 11.1

0.238

   Postdialytic PP (mmHg)

64.0 ± 13.8

72.6 ± 15.2

63.2 ± 11.4

57.5 ± 9.8

< 0.001*

Ultrafiltration volume (Kg)

2.4 ± 0.8

2.1 ± 0.5

2.3 ± 0.9

2.6 ± 0.8

0.006*

CT ratio > 50% (%)

68.7

89.7

63.0

55.1

0.002*

  1. Values are expressed as mean ± SD or percent unless otherwise listed. Abbreviations: ACE, angiotensin converting enzyme; ARB, angiotensin II-receptor blocker; ALT, alanine aminotransferase; Alk-P, alkaline phosphatase; HbA1c, glycosylated hemoglobin; WBC, white blood cell; CRP, C-reactive protein; SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, mean arterial pressure; PP, pulse pressure; CT, cardiothoracic. *: p < 0.05.