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Table 1 Baseline characteristics of patients with vertebral fracture in comparison with those without the fracture

From: Applicability of fibroblast growth factor 23 for evaluation of risk of vertebral fracture and chronic kidney disease-mineral bone disease in elderly chronic kidney disease patients

 

All

With-fracture group

Without-fracture group

pvalue

N (%)

105

11 (10.5)

94 (89.5)

 

Age (years)

73.2 (7.7)

79.0 (6.6)

72.5 (7.5)

0.008

Female (%)

34 (32.4)

5 (45.5)

29 (30.9)

0.33

Diabetes mellitus (%)

41 (39.0)

4 (36.4)

37 (39.4)

0.84

Height (cm)

159.5 (6.9)

161.1 (3.7)

159.2 (7.2)

0.41

Weight (kg)

61.3 (8.6)

63.2 (2.5)

61.0 (9.2)

0.44

BMI (kg/m2)

24.0 (2.5)

24.4 (1.5)

24.0 (2.6)

0.60

eGFR (ml/min/1.73 m2)

45.7 (24.1)

32.9 (18.8)

47.2 (24.3)

0.063

Calcium level (mmol/l)

2.4 (0.1)

2.3 (0.2)

2.4 (0.1)

0.85

Phosphate level (mmol/l)

1.1 (0.2)

1.1 (0.2)

1.1 (0.2)

0.81

Intact PTH level (ng/l)

143.6 (139.4) 96.2 (IQR, 65.8-154.4)

142.5 (79.3) 76 (IQR, 45–214)

143.6 (145.1) 91.3 (IQR, 65.1-154.4)

0.29

Ln(iPTH)

4.7 (0.7)

4.8 (0.5)

4.7 (0.7)

0.60

1,25(OH)2D level (pmol/l)

122.6 (54.6)

88.3 (49.0)

126.8 (54.0)

0.026

FGF23 level (pg/ml)

78.0 (101.7) 49.0 (IQR, 34.0-71.0)

136.2 (123.2) 120.7 (IQR, 82.2-179.1)

71.2 (97.4) 47 (IQR, 34–66)

0.012

Ln(FGF23)

4.0 (0.7)

4.6 (0.8)

3.9 (0.7)

0.005

ALP level (U/l)

227.0 (83.1)

252.1 (103.5)

224.1 (80.5)

0.29

Urinary NTX level (nmol.BCE/mmol.Cr)

35.8 (24.3)

36.9 (27.3)

35.6 (24.1)

0.88

  1. Values are expressed as mean (SD). The levels of intact PTH and FGF23 are presented with mean (SD), and median (IQR). The levels are compared between the groups by the chi-square test, t-test, or Mann–Whitney U test as appropriate.
  2. Abbreviations: with-fracture group, group with vertebral fracture; without-fracture group, group without vertebral fracture; BMI body mass index; eGFR estimated glomerular filtration rate; intact PTH intact parathyroid hormone; ln(iPTH) natural logarithm value of intact parathyroid hormone level; 1,25(OH) 2 D 1,25(OH)2 vitamin D; FGF23 fibroblast growth factor 23; ln(FGF23) natural logarithm value of fibroblast growth factor 23 level; ALP alkaline phosphatase; urinary NTX urinary N-terminal telopeptide; SD standard deviation; IQR interquartile range.