Table 3 Incidence of dementia estimated by comorbidity for CKD and non-CKD cohorts
| Â | Non-CKD | CKD | Â | |||
|---|---|---|---|---|---|---|
Comorbidity | Case | Incidence rate†| Case | Incidence rate†| HR | (95% CI) |
Hypertension | ||||||
No | 995 | 3.01 | 337 | 3.48 | 1.64 | (1.45-1.86) |
Yes | 1626 | 11.5 | 1676 | 14.02 | 1.48 | (1.38-1.58) |
Diabetes mellitus | ||||||
No | 2212 | 5.08 | 1203 | 7.83 | 1.52 | (1.42-1.64) |
Yes | 409 | 11.2 | 810 | 12.9 | 1.42 | (1.26-1.60) |
Ischemic heart disease | ||||||
No | 1680 | 4.23 | 921 | 6.05 | 1.63 | (1.50-1.76) |
Yes | 941 | 12.5 | 1092 | 17.0 | 1.52 | (1.39-1.65) |
Hyperlipidemia | ||||||
No | 2286 | 5.33 | 1491 | 9.36 | 1.65 | (1.54-1.78) |
Yes | 335 | 7.78 | 522 | 9.14 | 1.43 | (1.25-1.64) |
Tobacco use disorder | ||||||
No | 2620 | 5.55 | 2007 | 9.30 | 1.60 | (1.51-1.70) |
Yes | 1 | 1.81 | 6 | 11.1 | 6.73 | (0.81-56.1) |
Alcoholism | ||||||
No | 2608 | 5.54 | 1992 | 9.27 | 1.60 | (1.50-1.69) |
Yes | 13 | 8.72 | 21 | 14.8 | 2.88 | (1.41-5.91) |
Obesity | ||||||
No | 2614 | 5.56 | 2001 | 9.34 | 1.60 | (1.51-1.70) |
Yes | 7 | 3.13 | 12 | 5.32 | 2.81 | (1.04-7.58) |
Atrial fibrillation | ||||||
No | 2562 | 5.46 | 1929 | 9.03 | 1.59 | (1.50-1.69) |
Yes | 59 | 19.2 | 84 | 29.9 | 1.67 | (1.19-2.33) |
Parkinson's disease | ||||||
No | 2482 | 5.30 | 1876 | 8.78 | 1.61 | (1.51-1.71) |
Yes | 139 | 38.0 | 137 | 50.9 | 1.30 | (1.02-1.65) |
Cerebrovascular disease | ||||||
No | 1701 | 4.01 | 1048 | 5.89 | 1.59 | (1.47-1.72) |
Yea | 920 | 19.2 | 965 | 25.1 | 1.41 | (1.28-1.54) |
Major depressive disorder | ||||||
No | 2546 | 5.44 | 1949 | 9.15 | 1.61 | (1.51-1.71) |
Yes | 75 | 16.5 | 64 | 18.8 | 1.44 | (1.03-2.03) |