Table 2 Univariate analysis of parameters associated with renal function decline at 18 months (defined as a decrease in eGFR of at least 5 mL/min/ 1.73 m 2 /year or need for RRT) (Mann–Whitney and Fisher’s exact tests)
No decline | Decline | p | |
|---|---|---|---|
Number (%) of patients | 22 (63%) | 13 (37%) | |
Age (years) | 38 (23–68) | 55 (24–79) | 0.0035 |
Baseline eGFR (mL/min/1.73m 2 ) | 65 (17–108) | 12 (4–65) | 0.052 |
eGFR(mL/min/1.73m 2 ) at 18 months | 69 (24–123) | 8 (5–70) | 0.000015 |
SBP (mmHg) | 127 (98–160) | 129 (98–163) | 0.30 |
DBP (mmHg) | 77 (62–91) | 70 (59–96) | 0.89 |
Proteinuria/creatininuria (mg/mmol) | 96 (7–1216) | 492 (69–1742) | 0.049 |
% sclerotic glomeruli | 16 (0–71) | 4 (0–80) | 0.88 |
% interstitial fibrosis | 18 (0–80) | 18 (0–90) | 0.76 |
RI | 0.61 (0.31-0.70) | 0.69 (0.63-1.00) | 0.0023 |
Number (%) of patients with RI ≥ 0.65 | 4 (18%) | 10 (77%) | 0.0011 |