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Table 3 MCP-1 associations in the unadjusted and fully adjusted models

From: Relationships between serum MCP-1 and subclinical kidney disease: African American-Diabetes Heart Study

Outcome

Unadjusted

Adjusted

Estimate

StdErr

P-value

Estimate

StdErr

P-value

Log(Diabetes duration)

0.00060

0.00033

0.07

0.0003

0.0003

0.34

1/(HbA1c)

2.71E-06

1.248E-05

0.83

−7.70E-06

1.23E-05

0.53

1/sqrt(BMI)

−1.37E-05

8.53E-06

0.11

−2.02E-05

8.28E-06

0.01

Log(hsCRP)

0.0003

0.0006

0.54

−0.0001

0.0007

0.87

Log(CAC+1)

0.0006

0.001

0.57

−0.0003

0.0015

0.82

Log(CarCP+1)

0.0001

0.0008

0.86

−0.0012

0.0011

0.31

Log(AorCP+1)

0.0013

0.0012

0.25

−0.001

0.0015

0.48

Log(Urine ACR+1)

0.0013

0.0007

0.09

0.0021

0.001

0.04

Log(MDRD eGFR)

−0.0005

0.0001

<.0001

−0.0005

0.0001

0.006

Log(CKD-EPI eGFR)

−0.0004

0.0001

<.0001

−0.0003

0.0001

0.001

  1. MCP-1, monocyte chemoattractant protein-1; HbA1c, hemoglobin A1c; BMI, body mass index; hsCRP, high sensitivity C-reactive protein; CAC, coronary artery calcified plaque; CarCP, carotid artery calcified plaque; AorCP, infrarenal aorta calcified plaque; ACR, albumin: creatinine ratio; eGFR, estimated glomerular filtration rate.
  2. Adjusted model includes age, sex, smoking, HbA1c, BMI, and LDL-cholesterol.