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Figure 1 | BMC Nephrology

Figure 1

From: The effects of a selective inhibitor of c-Fos/activator protein-1 on endotoxin-induced acute kidney injury in mice

Figure 1

T-5224 attenuates LPS-induced TNF-α. a, determination of the point for TNF-α measurement. b, dose-dependent effects of T-5224 on TNF-α at 2 h after intraperitoneal LPS injection. Serum TNF-α levels peaked after LPS injection at 2 h (1583.8 ± 161.5 pg/ml). T-5224 attenuated LPS-induced TNF-α release dose-dependently (n = 7–8 per group). **P < 0.01 vs. control group. #P < 0.05 vs. LPS group. ##P < 0.01 vs. LPS group.

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