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Figure 2 | BMC Nephrology

Figure 2

From: Comparison of toxin removal outcomes in online hemodiafiltration and intra-dialytic exercise in high-flux hemodialysis: A prospective randomized open-label clinical study protocol

Figure 2

Diffusion-adjusted regional blood flow model (parallel-cum-series representation of physiology) or explaining β 2 -microglobulin kinetics. Toxin transfer is due to diffusion across capillary endothelium, and blood/plasma circulation causes convective transport. Q h/Q hp, Q l/Q lp, and Q b/Q bp are blood/plasma flows to high flow region (HFR), low flow region (LFR), and dialyzer, respectively. Q cr and Q ar are cardiopulmonary and access recirculation, respectively. Shaded compartments represent contact with blood (A – arterial node and V – venous node) [14].

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