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Table 2 Relations between clinical and histological variables at time of biopsy

From: Validation of the Oxford classification of IgA nephropathy for pediatric patients from China

 

MAP

eGFR

Proteinuria

Mesangial hypercellularity score (M)

 ≤0.5

87 ± 11

133 ± 43

1.2 (0.81-2.2)

 >0.5

90 ± 11

135 ± 40

1.9 (1.1-2.9)

 P-value

0.03

0.8

0.002

Endocapillary proliferation (E)

 Absent

87 ± 11

135 ± 42

1.3 (0.86-2.3)

 Present

90 ± 12

130 ± 43

2.1 (1.1-3.0)

 P-value

0.7

0.4

0.003

Segmental glomerulosclerosis (S-alone)

 Absent

85 ± 10

135 ± 43

1.2 (0.78-2.2)

 Present

92 ± 11

132 ± 41

1.7 (1.1-3.0)

 P-value

<0.001

0.7

<0.001

Segmental glomerulosclerosis or adhesion (S)

 Absent

86 ± 10

138 ± 41

1.2 (0.79-2.3)

 Present

90 ± 11

131 ± 42

1.6 (1.0-2.7)

 P-value

<0.001

0.3

0.01

Tubular atrophy / interstitial fibrosis (T)

 T0

87 ± 11

136 ± 41

1.4 (0.89-2.5)

 T1 or T2

96 ± 11

97 ± 44

2.4 (1.4-3.2)

 P-value

0.009

0.004

0.03

Crescent( C)

 Absent

87 ± 11

137 ± 42

1.2 (0.8-2.2)

 Present

90 ± 11

129 ± 42

1.8 (1.1-3.2)

 P-value

0.09

0.2

<0.001

Glomerulus necrosis (N)

 Absent

87 ± 11

135 ± 42

1.4 (0.9-2.5)

 Present

90 ± 12

125 ± 42

1.6 (0.9-2.9)

 P-value

0.4

0.2

0.3

  1. Abbreviations:eGFR, estimated glomerular filtration rate; MAP, mean arterial pressure.
  2. Values are expressed as mean ± s.d. or median (interquartile range). Calculation of MAP, eGFR, and proteinuria is detailed in the text.