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Table 2 Relations between clinical and histological variables at time of biopsy

From: Validation of the Oxford classification of IgA nephropathy for pediatric patients from China

  MAP eGFR Proteinuria
Mesangial hypercellularity score (M)
 ≤0.5 87 ± 11 133 ± 43 1.2 (0.81-2.2)
 >0.5 90 ± 11 135 ± 40 1.9 (1.1-2.9)
 P-value 0.03 0.8 0.002
Endocapillary proliferation (E)
 Absent 87 ± 11 135 ± 42 1.3 (0.86-2.3)
 Present 90 ± 12 130 ± 43 2.1 (1.1-3.0)
 P-value 0.7 0.4 0.003
Segmental glomerulosclerosis (S-alone)
 Absent 85 ± 10 135 ± 43 1.2 (0.78-2.2)
 Present 92 ± 11 132 ± 41 1.7 (1.1-3.0)
 P-value <0.001 0.7 <0.001
Segmental glomerulosclerosis or adhesion (S)
 Absent 86 ± 10 138 ± 41 1.2 (0.79-2.3)
 Present 90 ± 11 131 ± 42 1.6 (1.0-2.7)
 P-value <0.001 0.3 0.01
Tubular atrophy / interstitial fibrosis (T)
 T0 87 ± 11 136 ± 41 1.4 (0.89-2.5)
 T1 or T2 96 ± 11 97 ± 44 2.4 (1.4-3.2)
 P-value 0.009 0.004 0.03
Crescent( C)
 Absent 87 ± 11 137 ± 42 1.2 (0.8-2.2)
 Present 90 ± 11 129 ± 42 1.8 (1.1-3.2)
 P-value 0.09 0.2 <0.001
Glomerulus necrosis (N)
 Absent 87 ± 11 135 ± 42 1.4 (0.9-2.5)
 Present 90 ± 12 125 ± 42 1.6 (0.9-2.9)
 P-value 0.4 0.2 0.3
  1. Abbreviations:eGFR, estimated glomerular filtration rate; MAP, mean arterial pressure.
  2. Values are expressed as mean ± s.d. or median (interquartile range). Calculation of MAP, eGFR, and proteinuria is detailed in the text.