Validation of the Oxford classification of IgA nephropathy for pediatric patients from China

BMC Nephrology

Table 4 Correlations between pathological features and outcomes

	HR (95% CI) Univariate	P-value	HR (95% CI) Multivariate^b	P-value
Mesangial hypercellularity score (M)
≤0.5	1.0	0.1	1.0	0.6
>0.5	2.1 (0.84-5.1)	0.1	1.3 (0.49-3.4)	0.6
Endocapillary proliferation (E)
Absent	1.0	0.5	1.0	0.2
Present	0.67 (0.2-2.3)	0.5	0.44 (0.12-1.5)	0.2
Segmental glomerulosclerosis or adhesion (S)
Absent	1.0	0.03	1.0	0.1
Present	9.2 (1.2-68.6)	0.03	5.2 (0.6-43)	0.1
Tubular atrophy / interstitial fibrosis (T)
T0	1.0	0.01	1.0	0.04
T1 or T2	4.3 (1.8-10.5)	0.01	2.9 (1.0-7.9)	0.04
Crescent (C)
Absent	1.0	0.2		NS
Present	1.8 (0.8-4.1)	0.2		NS

Abbreviations: CI, confidence interval; OR, odds ratio; HR, hazard ratio. NS, not significant.
^bMultivariate Cox regression model: multivariate with four pathological features (M,E,S,T) + initial eGFR, MAP and proteinuria.

ISSN: 1471-2369