Table 2 Multivariable logistic regression analysis of predictors of ESKD due to HUS, as opposed to other causes of ESKD, in both the entire cohort (limited covariate adjustment) and a contemporary cohort in which complete data were available on comorbidities
Characteristic | Entire cohort (1963–2010) (n = 58442) | Contemporary cohort (1996–2010) (n = 36884) |
|---|---|---|
Age (per decade) | 0.54 (0.50-0.57) | 0.63 (0.57-0.69) |
Male gender | 0.40 (0.31-0.52) | 0.40 (0.28-0.57) |
Racial origin | ||
European | Reference | Reference |
ATSI | 0.18 (0.07-0.47) | 0.26 (0.08-0.85) |
MPI | 0.26 (0.13-0.52) | 0.33 (0.14-0.77) |
Asian | 0.40 (0.18-0.92) | 0.37 (0.15-0.91) |
Other | NS | 0.42 (0.15-1.15) |
RRT era | NS | |
1963–1975 | 0.36 (0.19-0.66) | |
1976–1985 | 0.55 (0.36-0.85) | |
1986–1995 | 0.53 (0.36- 0.80) | |
1996–2000 | 1.03 (0.69-1.51) | |
2001–2005 | 0.86 (0.57-1.28) | |
2006-2010 | Reference | |
Ever smoked | NA | NS |
Diabetes mellitus | NA | 0.13 (0.06-0.31) |
Chronic lung disease | NA | NS |
Coronary artery disease | NA | NS |
Peripheral vascular disease | NA | NS |
Cerebrovascular disease | NA | NS |
BMI (kg/m2) | NA | NS |
Late referral | NA | 3.72 (2.65-5.22) |