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Table 3 Characteristics of all patients with ESKD secondary to HUS or other causes in Australia and New Zealand who underwent renal transplantation during the period 1963–2010, before and after matching for age, gender and transplant era

From: End-stage kidney disease due to haemolytic uraemic syndrome – outcomes in 241 consecutive ANZDATA registry cases

 

Before matching

After matching

Characteristic

HUS ESKD (n = 130)

Other ESKD (n = 19549)

P value

Other ESKD Control (n = 130)

P value

Age

25.2 ± 17.1

41.9 ± 14.8

<0.001

25.2 ± 17.0

0.98

Male gender

52 (40%)

11704 (60%)

0.001

52 (40%)

1.00

Racial origin

  

0.1

 

0.01

  European

118 (91%)

16738 (86%)

 

104 (80%)

 

  ATSI

1 (1%)

489 (3%)

 

3 (2%)

 

  MPI

4 (3%)

812 (4%)

 

11 (9%)

 

  Asian

1 (1%)

925 (5%)

 

9 (7%)

 

  Other

6 (5%)

585 (3%)

 

3 (2%)

 

Transplant era

  

0.01

 

1.00

  1963–1975

4(3%)

1939 (10%)

 

4 (3%)

 

  1976–1985

23 (18%)

3448 (18%)

 

22 (17%)

 

  1986–1995

22 (17%)

4595 (24%)

 

22 (17%)

 

  1996–2000

26 (20%)

2667 (14%)

 

27 (21%)

 

  2001–2005

24 (19%)

3150 (16%)

 

24 (19%)

 

  2006-2009

31 (24%)

3750 (19%)

 

31 (24%)

 

Ever smoked

  

<0.001

 

0.37

  Current

10 (8%)

1560 (8%)

 

4 (3%)

 

  Former

14 (11%)

3668 (19%)

 

15 (12%)

 

  Never

82 (63%)

7788 (40%)

 

90 (69%)

 

  Missing

24 (19%)

6533 (33%)

 

21 (16%)

 

Hypertension

  

0.009

 

0.35

  Yes

54 (42%)

8562 (44%)

 

43 (33%)

 

  No

23 (18%)

1898 (10%)

 

24 (19%)

 

  Missing

53 (41%)

9089 (47%)

 

63 (49%)

 

Diabetes mellitus

  

<0.001

 

0.007

  Yes

1 (1%)

2098 (11%)

 

11 (9%)

 

  No

113 (87%)

13435 (69%)

 

109 (84%)

 

  Missing

16 (12%)

4016 (21%)

 

10 (8%)

 

Chronic lung disease

  

0.007

 

0.28

  Yes

1 (1%)

581 (3%)

 

1 (1%)

 

  No

111 (85%)

14333 (73%)

 

119 (92%)

 

  Missing

18 (14%)

4637 (24%)

 

10 (8%)

 

Coronary artery disease

  

0.002

 

0.25

  Yes

4 (3%)

1201 (6%)

 

3 (2%)

 

  No

108 (83%)

13484(69%)

 

117 (90%)

 

  Missing

18 (14%)

4864 (25%)

 

10 (8%)

 

Peripheral vascular disease

  

0.003

 

0.28

  Yes

1 (1%)

703 (4%)

 

1 (1%)

 

  No

111 (85%)

14137 (72%)

 

119 (92%)

 

Missing

18 (14%)

4709 (24%)

 

10 (8%)

 

Cerebrovascular disease

  

0.025

 

0.03

  Yes

4 (3%)

391 (2%)

 

0 (0%)

 

  No

108 (83%)

14525(74%)

 

120 (92%)

 

  Missing

18 (14%)

4633 (24%)

 

10 (8%)

 

BMI (kg/m2)

  

<0.001

 

0.86

Late referral

22.0 ± 5.9

24.7 ± 5.1

<0.001

21.8 ± 5.9

0.001

  Yes

35 (27%)

1742 (9%)

 

15 (12%)

 

  No

56 (43%)

10294 (53%)

 

84 (65%)

 

  Missing

39 (30%)

7513 (38%)

 

31 (24%)

 

Donor type

  

<0.001

 

1.00

  Deceased

72 (55%)

14540 (74%)

 

72 (55%)

 

  Living

58 (45%)

5009 (26%)

 

58 (45%)

 

Subsequent grafts

  

0.06

 

0.44

  2

32 (19%)

2718 (12%)

 

22 (14%)

 

  3

3 (2%)

440 (2%)

 

4 (3%)

 

  4

1 (0%)

61 (0%)

 

0 (0%)

 

  5

0 (0%)

5 (0%)

 

0 (0%)

 
  1. Abbreviations: ATSI Aboriginal and Torres Strait Islander, BMI Body mass index, MPI Maori and Pacific Islander, RRT Renal replacement therapy.