From: Risk factors affecting seroconversion after influenza A/H1N1 vaccination in hemodialysis patients
Variables | All patients (n = 97) | Nonresponders (n = 67) | Responders (n = 30) | P-value |
---|---|---|---|---|
Age (years) | 60.9 ± 12.6 | 63.1 ± 12.0 | 56.3 ± 12.6 | 0.012 |
Sex (Male,%) | 54 (56.7) | 35 (53.0) | 19 (61.3) | 0.445 |
Diabetes Mellitus (%) | 62 (63.9) | 44 (65.7) | 18 (60.0) | 0.591 |
Body mass index (Kg/m2) | 22.7 ± 3.5 | 22.7 ± 3.6 | 22.8 ± 3.4 | 0.898 |
Duration of dialysis (mo)* | 41.0 (25–41) | 37.5 (22.8-66.3) | 53.0 (31.0-82.0) | 0.082 |
KT/V | 1.44 ± 0.32 | 1.44 ± 0.33 | 1.41 ± 0.28 | 0.705 |
Urea reduction rate (%) | 69.3 ± 7.9 | 70.0 ± 7.8 | 67.8 ± 8.2 | 0.193 |
Hepatitis B or C (%) | 8 (8.2) | 5 (7.5) | 3 (10.0) | 0.708 |
Medications (%) | Â | Â | Â | Â |
Angiotensin converting enzyme inhibitor | 18 (18.6) | 11 (16.4) | 7 (23.3%) | 0.418 |
Angiotensin II receptor blocker | 60 (61.9) | 37 (55.2) | 23 (76.7) | 0.044 |
Calcium channel blocker | 60 (61.9) | 41 (61.2) | 19 (63.3) | 0.841 |
Beta blocker | 49 (50.5) | 30 (44.8) | 19 (63.3) | 0.194 |
Diuretics | 53 (54.6) | 38 (56.7) | 15 (50.0) | 0.539 |
Statins | 40 (42.3) | 28 (41.8) | 12 (40.0) | 0.868 |
Vitamin D analogue | 5 (5.2) | 4 (6.0) | 1 (3.3) | 0.587 |
White blood cell (/mm3) | 6,450 ± 1,846 | 6,490 ± 1,977 | 6,368 ± 1,561 | 0.765 |
Lymphocyte count (/mm3) | 1,376 ± 547 | 1,432 ± 568 | 1,225 ± 479 | 0.313 |
Hemoglobin (g/dL) | 10.2 ± 1.1 | 10.0 ± 1.14 | 10.5 ± 0.85 | 0.032 |
MCV (fL) | 93.7 ± 5.1 | 94.4 ± 5.3 | 91.4 ± 3.6 | 0.075 |
MCH (pg) | 30.9 ± 1.7 | 31.1 ± 1.7 | 30.4 ± 1.3 | 0.153 |
MCHC (g/dL) | 33.1 ± 1.1 | 33.0 ± 1.1 | 33.2 ± 1.1 | 0.546 |
Ferritin (ng/mL)* | 159 (107–255) | 159 (98–255) | 155 (108–259) | 0.367 |
C-reactive protein (mg/L)* | 1.1 (0.5-4.7) | 1.1 (0.5-4.3) | 2.5 (0.45-6.1) | 0.446 |
Glucose (mg/dL) | 133 ± 48 | 134 ± 48 | 130 ± 48 | 0.74 |
Uric acid (mg/dL) | 7.3 ± 1.3 | 7.2 ± 1.3 | 7.4 ± 1.4 | 0.241 |
Total Cholesterol (mg/dL) | 149 ± 35 | 153 ± 40 | 149 ± 27 | 0.477 |
Albumin (g/dL) | 4.0 ± 0.4 | 4.0 ± 0.4 | 4.0 ± 0.3 | 0.874 |
Alkaline phosphatase (IU/L) | 91 ± 55 | 84 ± 50 | 101 ± 62 | 0.170 |
Total bilirubin (mg/dL) | 0.31 ± 0.14 | 0.32 ± 0.15 | 0.29 ± 0.12 | 0.422 |
Triglyceride (mg/dL) | 129 ± 94 | 133 ± 106 | 117 ± 60 | 0.351 |
HDL-cholesterol (mg/dL) | 38 ± 13 | 37 ± 13 | 41 ± 14 | 0.332 |
Intact-parathyroid hormone (pg/mL) | 160 ± 97 | 148 ± 96 | 188 ± 97 | 0.069 |