Figure 3
From: Disruption of the endothelin A receptor in the nephron causes mild fluid volume expansion
Representative photomicrographs of kidneys from Pax8-rtTA/LC1/floxed ETA (iETA) mice before and after doxycycline (DOX) treatment. Panel A shows cortex and Panel B shows medulla prior to DOX treatment; Panel C shows cortex after DOX treatment. DOX-treated iETA medullary staining is not shown since ETA immunostaining was not apparent in untreated iETA mice. Arrows indicate blood vessels. Staining was performed on 6 different mice of each genotype. Images are 200X.