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Table 1 Characteristics of the study population

From: Association between serum insulin-like growth factor I or IGF-binding protein 3 and estimated glomerular filtration rate: results of a population-based sample

   Characteristics

Men

Women

p

(n = 1980)

(n = 2048)

Age (years)

52 (37; 65)

49 (36; 62)

<0.01

Waist circumference (cm)

95.2 (87.5; 103.0)

81.5 (72.8; 92.2)

<0.01

Physical activity (%)

41.5

43.7

0.17

Current smoker (%)

33.2

27.2

<0.01

Type 2 diabetes mellitus (%)

8.7

7.4

0.12

Hypertension (%)

62.7

41.7

<0.01

Serum IGF-I (ng/mL)

131 (103; 168)

134 (101; 172)

0.36

Serum IGFBP-3 (ng/mL)

1795 (1473; 2110)

1971 (1666; 2279)

<0.01

Serum creatinine (mg/dL)

1.02 (0.94; 1.12)

0.87 (0.80; 0.94)

<0.01

eGFR (mL/min/1.73m2)

83.02 (73.54; 92.97)

74.84 (66.83; 84.51)

<0.01

CKD (%)

6.6

11.1

<0.01

  1. Continuous data are given as median (25th; 75th quartile); nominal data are given as percentages. χ2-test (nominal data) or Kruskal-Wallis test (interval data). IGF-I = insulin-like growth factor I; IGFBP-3 = insulin-like growth factor-binding protein 3; eGFR = estimated glomerular filtration rate; CKD = chronic kidney disease defined as eGFR < 60 ml/min/1.73 m2.