Impact of heavy proteinuria on clinical outcomes in patients on incident peritoneal dialysis

BMC Nephrology

Table 2 Changes in the variables from the time of peritoneal dialysis initiation to the end of follow-up period: comparison of the 3 groups according to initial proteinuria levels

	A group	B group	C group	P value*
Delta GNRI	3.47 ± 6.54^a	1.92 ± 6.63^a	6.97 ± 8.52^b	<0.001
Delta RRF (mL/min/1.73 m²)	0.00 (−9.99 to 7.10)^a	−0.81 (−7.88 to 6.58)^a	−2.41 (−23.41 to 2.31)^b	<0.001
Delta nPNA	0.04 ± 0.23	0.05 ± 0.23	0.06 ± 0.24	0.898
Delta MAP	4.4 ± 16.3	3.2 ± 17.1	8.6 ± 15.4	0.483
Delta total lean mass index	0.47 ± 1.19	0.10 ± 1.23	−0.07 ± 2.56	0.198
Delta total fat mass index	0.76 ± 1.03	0.75 ± 1.87	1.20 ± 1.49	0.418
Delta peritoneal albumin loss (mg/day)	−233 ± 995	−59 ± 1370	324 ± 1477	0.075
Delta proteinuria (mg/day)	197 ± 648^a	−475 ± 945^a	−4626 ± 5466^b	<0.001

The data are expressed as numbers (percentages) for the categorical variables and median (range) or mean ± standard deviation for the continuous variables.
*Statistical significance was tested by one-way analysis of variance or Kruskal-Wallis test for the continuous variables and the Pearson χ² test or Fisher exact test for the categorical variables. The different superscripts (^a,b,c) indicate significant differences from each other using post hoc Tukey comparison or Bonferroni correction.
GNRI, geriatric nutritional risk index; RRF, residual renal function; nPNA, normalized protein equivalent of nitrogen appearance; MAP, mean arterial pressure.

ISSN: 1471-2369