|  | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|---|
 |  | Unadjusted OR (95% CI) | P | Adjusted OR (95% CI) | P |
Age (year) | < 40 | Reference | Â | Reference | Â |
 | 40-60 | 2.205 (1.910-2.545) | < 0.001 | 1.598 (1.345-1.879) | < 0.001 |
 | ≥ 60 | 9.573 (8.117-11.289) | < 0.001 | 3.337 (2.598-4.287) | < 0.001 |
Male | Male | 0.569 (0.508-0.638) | < 0.001 | 0.569 (0.487-0.666) | < 0.001 |
eGFR | ≥ 90.0 | Reference |  | Reference |  |
 | 60.0-89.9 | 1.994 (1.639-2.426) | < 0.001 | 1.168 (0.929-1.469) | 0.185 |
 | 30.0-59.9 | 10.372 (7.868-13.672) | < 0.001 | 1.531 (1.077-2.176) | 0.018 |
Diabetes mellitus | Yes | 2.140 (1.747-2.622) | < 0.001 | Â | Â |
Hypertension | Yes | 2.554 (2.252-2.895) | < 0.001 | 1.231 (1.048-1.445) | 0.011 |
Metabolic syndrome | Yes | 2.091 (1.853-2.358) | < 0.001 | Â | Â |
Ischemic heart disease | Yes | 8.419 (5.184-13.675) | < 0.001 | 3.730 (2.169-6.415) | < 0.001 |
Cerebrovascular accident | yes | 3.349 (3.505-8.164) | < 0.001 | 1.971 (1.194-3.256) | 0.008 |
Alcohol intake | ≥ 1/week | 0.652 (0.576-0.737) | < 0.001 |  |  |
Smoking status | life-time smoker | 0.789 (0.703-0.886) | < 0.001 | Â | Â |
Marital status | without spouse | 1.290 (1.141-1.458) | < 0.001 | Â | Â |
Occupation | white collar | Reference | Â | Reference | Â |
 | blue collar | 2.545 (2.184-2.965) | < 0.001 | 1.400 (1.154-1.689) | 0.001 |
 | other†| 1.944 (1.661-2.275 | < 0.001 | 1.328 (1.097-1.608) | 0.004 |
 | no occupation | 4.953 (4.148-5.914) | < 0.001 | 1.741 (1.378-2.199) | < 0.001 |
Education | ≥ university | Reference |  | Reference |  |
 | upper 2ndary‡ | 1.886 (1.608-2.213) | < 0.001 | 1.294 (1.076-1.555) | 0.006 |
 | ≤ compulsory§ | 9.607 (8.035-11.488) | <0.001 | 2.515 (1.970-3.212) | < 0.001 |
Income | highest quartile | Reference | Â | Reference | Â |
 | 2nd -3rd quartile | 1.432 (1.224-1.674) | < 0.001 | 1.139 (0.953-1.360) | 0.152 |
 | lowest quartile | 4.735 (3.986-5.625) | < 0.001 | 1.676 (1.356-2.072) | < 0.001 |
Residence | rural residence | 2.056 (1.808-2.339) | < 0.001 | 1.190 (1.011-1.401) | 0.036 |
Stress | some or extreme | 1.752 (1.559-1.968) | < 0.001 | 1.753 (1.525-2.016) | < 0.001 |
Sleep quality | insufficient | 1.276 (1.137-1.432) | < 0.001 | 1.606 (1.396-1.848) | < 0.001 |