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Table 3 Univariate and multivariate logistic regression analyses for impaired HRQOL

From: The association of moderate renal dysfunction with impaired preference-based health-related quality of life: 3rdKorean national health and nutritional examination survey

   Univariate analysis Multivariate analysis
   Unadjusted OR (95% CI) P Adjusted OR (95% CI) P
Age (year) < 40 Reference   Reference  
  40-60 2.205 (1.910-2.545) < 0.001 1.598 (1.345-1.879) < 0.001
  ≥ 60 9.573 (8.117-11.289) < 0.001 3.337 (2.598-4.287) < 0.001
Male Male 0.569 (0.508-0.638) < 0.001 0.569 (0.487-0.666) < 0.001
eGFR ≥ 90.0 Reference   Reference  
  60.0-89.9 1.994 (1.639-2.426) < 0.001 1.168 (0.929-1.469) 0.185
  30.0-59.9 10.372 (7.868-13.672) < 0.001 1.531 (1.077-2.176) 0.018
Diabetes mellitus Yes 2.140 (1.747-2.622) < 0.001   
Hypertension Yes 2.554 (2.252-2.895) < 0.001 1.231 (1.048-1.445) 0.011
Metabolic syndrome Yes 2.091 (1.853-2.358) < 0.001   
Ischemic heart disease Yes 8.419 (5.184-13.675) < 0.001 3.730 (2.169-6.415) < 0.001
Cerebrovascular accident yes 3.349 (3.505-8.164) < 0.001 1.971 (1.194-3.256) 0.008
Alcohol intake ≥ 1/week 0.652 (0.576-0.737) < 0.001   
Smoking status life-time smoker 0.789 (0.703-0.886) < 0.001   
Marital status without spouse 1.290 (1.141-1.458) < 0.001   
Occupation white collar Reference   Reference  
  blue collar 2.545 (2.184-2.965) < 0.001 1.400 (1.154-1.689) 0.001
  other 1.944 (1.661-2.275 < 0.001 1.328 (1.097-1.608) 0.004
  no occupation 4.953 (4.148-5.914) < 0.001 1.741 (1.378-2.199) < 0.001
Education ≥ university Reference   Reference  
  upper 2ndary 1.886 (1.608-2.213) < 0.001 1.294 (1.076-1.555) 0.006
  ≤ compulsory§ 9.607 (8.035-11.488) <0.001 2.515 (1.970-3.212) < 0.001
Income highest quartile Reference   Reference  
  2nd -3rd quartile 1.432 (1.224-1.674) < 0.001 1.139 (0.953-1.360) 0.152
  lowest quartile 4.735 (3.986-5.625) < 0.001 1.676 (1.356-2.072) < 0.001
Residence rural residence 2.056 (1.808-2.339) < 0.001 1.190 (1.011-1.401) 0.036
Stress some or extreme 1.752 (1.559-1.968) < 0.001 1.753 (1.525-2.016) < 0.001
Sleep quality insufficient 1.276 (1.137-1.432) < 0.001 1.606 (1.396-1.848) < 0.001
  1. Values shown are OR (95% CI). Impaired HRQOL was defined as the lowest quartile of EQ-5D weighted values. Potential risk factors in the unadjusted analysis (P < 0.05) were included in the adjusted analysis. The multivariate logistic regression analysis model was derived using the backward conditional method. †Students, soldiers and housewives; ‡middle and high school graduates; §elementary school or no education. HRQOL, health-related quality of life; eGFR, estimated glomerular filtration rate (mL/min/1.73 m2); OR, odds ratio; CI; confidence interval