Skip to main content

Advertisement

Table 3 Model 2. Relation of lnFGF23 in the full adjusted model with cardiovascular and renal risk factors

From: Fibroblast growth factor 23 is associated with proteinuria and smoking in chronic kidney disease: An analysis of the MASTERPLAN cohort

Variable B Standard error Beta p-value
eGFR (MDRD, ml/min/1.73 m 2 ) -0.022 0.003 -034 < 0.001
Phosphate (mmol/l) 0.297 0.131 0.082 0.024
lnPTH (pmol/l) 0.244 0.047 0.196 < 0.001
Calcium (mmol/l) 0.393 0.220 0.062 0.075
Proteinuria (gram/24 hours) 0.064 0.021 0.113 0.002
Male -0.094 0.071 -0.048 0.183
Smoking 0.313 0.073 0.148 < 0.001
BMI 0.003 0.007 0.017 0.638
Diabetes Mellitus 0.159 0.075 0.075 0.035
History CVD 0.224 0.071 0.113 0.002
Age (year) 0.001 0.003 0.006 0.868
Systolic blood pressure (mmHg) -0.001 0.002 -0.02 0.586
Total cholesterol (mmol/l) 0.006 0.031 0.007 0.848
Active vitamin D use 0.096 0.079 0.044 0.223
  1. Model 2: multivariable analyses of relation of lnFGF23 with Framingham risk factors (model 1) and renal risk factors. B reflects change in lnFGF23 per unit change in the variable. For dichotomous variables (sex, smoking, diabetes, and history of CVD) B reflects lnFGF23 change in the presence of the depicted variable. Beta is the standardized B to compare influence on lnFGF23 between variables.
  2. eGFR: estimated glomerular filtration rate; MDRD: four-point MDRD-formula; BMI: Body mass index; CVD: cardiovascular disease