|
Variable
|
B
|
Standard error
|
Beta
|
p-value
|
|---|
|
eGFR (MDRD, ml/min/1.73 m
2
)
|
-0.022
|
0.003
|
-034
|
< 0.001
|
|
Phosphate (mmol/l)
|
0.297
|
0.131
|
0.082
|
0.024
|
|
lnPTH (pmol/l)
|
0.244
|
0.047
|
0.196
|
< 0.001
|
|
Calcium (mmol/l)
|
0.393
|
0.220
|
0.062
|
0.075
|
|
Proteinuria (gram/24 hours)
|
0.064
|
0.021
|
0.113
|
0.002
|
|
Male
|
-0.094
|
0.071
|
-0.048
|
0.183
|
|
Smoking
|
0.313
|
0.073
|
0.148
|
< 0.001
|
|
BMI
|
0.003
|
0.007
|
0.017
|
0.638
|
|
Diabetes Mellitus
|
0.159
|
0.075
|
0.075
|
0.035
|
|
History CVD
|
0.224
|
0.071
|
0.113
|
0.002
|
|
Age (year)
|
0.001
|
0.003
|
0.006
|
0.868
|
|
Systolic blood pressure (mmHg)
|
-0.001
|
0.002
|
-0.02
|
0.586
|
|
Total cholesterol (mmol/l)
|
0.006
|
0.031
|
0.007
|
0.848
|
|
Active vitamin D use
|
0.096
|
0.079
|
0.044
|
0.223
|
- Model 2: multivariable analyses of relation of lnFGF23 with Framingham risk factors (model 1) and renal risk factors. B reflects change in lnFGF23 per unit change in the variable. For dichotomous variables (sex, smoking, diabetes, and history of CVD) B reflects lnFGF23 change in the presence of the depicted variable. Beta is the standardized B to compare influence on lnFGF23 between variables.
- eGFR: estimated glomerular filtration rate; MDRD: four-point MDRD-formula; BMI: Body mass index; CVD: cardiovascular disease
