Figure 1

Comparison of urinary protein markers between children with mild and severe renal histological lesions. Comparison of urinary proteins between children with severe mesangial cellularity (MC) defined as > 5 mesangial cells/ mesangial area (score ≥ 2, n = 34) and those with mild MC (score < 2, n = 64); between children with severe glomerulosclerosis (GS) defined as ≥ 10 % glomeruli showing segmental adhesions or sclerosis (score ≥ 2, n = 17) and those with mild GS (score < 2, n = 81); and between children with severe tubule-interstitial damage (TID) defined as focal or diffuse tubular and interstitial lesions (score ≥ 2, n = 20) and those with mild TID (score < 2, n = 78). Urinary excretion of IgG (A), albumin (B), transferrin (C), NAG (D), α1-microglobulin (E) and β2-microglobulin (F) was log transformed. Values are medians, boxes represent interquartile range, whiskers indicate smallest and largest non-outlier observation, and circles indicate outliers. Probability values: two-sample Kolmogorov-Smirnov test, *p < 0.05.